M Wt. 252
Formula: C₁₁ H₁₂ N₂ O S₂

Phenotype

 

Descriptor

Anatomical Features DO7895

Axis	Reduced length, curved ventrally
Blood	Absent
Blood circulation	Absent
Brain	Increased size
Cloaca	Swollen
Eye	Normal
Eye pigmentation	Absent
Forebrain	Normal
Fourth ventricle	Swollen
Head	Swollen, increased size
Heart	Increased size
Heart contraction	Movement-loss
Locomotion	Movement-loss
Melanocyte	Absent
Midbrain hindbrain boundary	Normal
Notochord	Wavy
Otic placode	Reduced size
Otolith	Increased amount
Pericardium	Swollen
Post-vent region	Reduced amount, absent
Somite	Abnormal
Third Ventricle	Swollen
Trunk	Reduced length, increased width
Tail	Reduced length
Whole organism	Reduced length, increased width
Yolk	Increased amount

Cheminformatics

Molinspiration

Bioactivity score v2016.03

GPCR ligand                     -0.64
Ion channel modulator      -0.49
Kinase inhibitor                 -0.90
Nuclear receptor ligand    -1.41
Protease inhibitor              -0.67
Enzyme inhibitor               -0.53

ChemProt TC>0.97

Target: Potency

Lasso

Category	Target	PDB ID	Score
Kinases	PDGFrb, platelet derived growth factor receptor kinase	N/A	0.24
Nuclear Hormone Receptors	PPARg, peroxisome proliferator activated receptor	1fm9	0.03
Other Enzymes	HIVRT, HIV reverse transcriptase	1rt1	0.02

Confirmed Pathway Activity

 

Confirmed Targets

 

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