{"id":187,"date":"2018-08-21T13:59:04","date_gmt":"2018-08-21T18:59:04","guid":{"rendered":"https:\/\/my.vanderbilt.edu\/janosmathe\/?page_id=187"},"modified":"2018-08-21T17:18:33","modified_gmt":"2018-08-21T22:18:33","slug":"clinical-decision-support","status":"publish","type":"page","link":"https:\/\/my.vanderbilt.edu\/janosmathe\/publications\/clinical-decision-support\/","title":{"rendered":"Clinical Decision Support Applications"},"content":{"rendered":"<p><font size=\"2\">Edited on 2018-08-21<\/font><\/p>\n<p><a href=\"https:\/\/my.vanderbilt.edu\/janosmathe\/publications\"><strong>&lt;<\/strong> Back to Publications<\/a><\/p>\n<h3>Summary<\/h3>\n<div style=\"text-align: justify\">\nMy work in clinical decision support has focused on two application areas of computer interpretable guidelines: plan-based and state-based (i.e. reactive) patient management systems. The later work focused on creating a prototype system for the detection and management of sepsis in a multiple intensive care unit (ICU) setting. The former work targeted the creation of a tool suite to enable longitudinal cancer treatment plan management with the intent of standardizing care, improving safety and efficiency, and providing agility and scaling in terms of knowledge representation and dissemination. Using formal methods and highly motivated interdisciplinary teams, we have delivered dedicated clinical applications through which we increased compliance to best practice guidelines.\n<\/div>\n<h3>Featured Projects<\/h3>\n<ul>\n<li><a href=\"https:\/\/my.vanderbilt.edu\/janosmathe\/projects\/vois\">Vanderbilt Oncology Information System (VOIS)<\/a><\/li>\n<li><a href=\"https:\/\/my.vanderbilt.edu\/janosmathe\/projects\/sepsis-treatment-management-tool\">Sepsis Treatment Enhanced through Electronic Protocolization (STEEP)<\/a><\/li>\n<\/ul>\n<h3>Publications<\/h3>\n<p>Mathe, J.L.; Levy, M. <a href=\"https:\/\/www.researchgate.net\/publication\/326522059_The_ephemeral_life_of_the_computer_interpretable_guideline-driven_Vanderbilt_Oncology_Information_System\"><font color=\"#009922\">The ephemeral life of the computer interpretable, guideline-driven Vanderbilt Oncology Information System<\/font><\/a>. Presented at the Mobilizing Computable Biomedical Knowledge (MCBK) Summer Meeting, National Library of Medicine (NLM), Bethesda, MD, p. 1 <strong>2018<\/strong>.<\/p>\n<p>Mathe, J.L. <a href=\"https:\/\/mediasite.vanderbilt.edu\/Mediasite\/Play\/e1376a0fe5714dfea0ea8faba733681d1d\"><font color=\"#009922\">Practical Knowledge Engineering for Clinical Decision Support<\/font><\/a>. Presented at the Biomedical Informatics Seminar, Vanderbilt University <strong>2018<\/strong>.<\/p>\n<p>Mathe, J.L. <a href=\"http:\/\/etd.library.vanderbilt.edu\/available\/etd-11192012-144514\/\"><font color=\"#009922\">The Precise Construction of Patient Protocols: Modeling, Simulation and Analysis of Computer Interpretable Guidelines<\/font><\/a>. Vanderbilt University, Nashville, TN <strong>2012<\/strong>.<\/p>\n<p>Hooper, M.H.; Weavind, L.; Wheeler, A.P.; Martin, J.B.; Gowda, S.S.; Semler, M.W.; Hayes, R.M.; Albert, D.W.; Deane, N.B.; Nian, H.; Mathe, J.L.; Nadas, A.; Sztipanovits, J.; Miller, A.; Bernard, G.R.; Rice, T.W. <font color=\"#009922\">Randomized Trial of Automated, Electronic Monitoring to Facilitate Early Detection of Sepsis in the Intensive Care Unit<\/font>. Crit. Care Med. In press, 2096\u20132101 <strong>2012<\/strong>.<\/p>\n<p>Mathe, J.L.; Sztipanovits, J.; Levy, M.; Jackson, E.K.; Schulte, W. <a href=\"http:\/\/ieeexplore.ieee.org\/xpl\/articleDetails.jsp?arnumber=6227014\"><font color=\"#009922\">Cancer Treatment Planning: Formal Methods to the Rescue<\/font><\/a>, in: 4rd International Workshop on Software Engineering in Health Care (SEHC 2012). Presented at the SEHC 2012 Workshop @ ICSE, Zurich, Switzerland <strong>2012<\/strong>.<\/p>\n<p>Mathe, J.L.; Werner, J.; Sztipanovits, J. <a href=\"https:\/\/books.google.com\/books?hl=en&amp;lr=&amp;id=LjAs2Jrco00C&amp;oi=fnd&amp;pg=PR5&amp;ots=bys-T-pN_V&amp;sig=VuLf4WI-6VY-nGQqW0YMfNY9U54#v=onepage&amp;q&amp;f=false\"><font color=\"#009922\">Model-Based Design of Trustworthy Health Information Systems<\/font><\/a>, in: Homeland Security Facets: Threats. Countermeasures, and the Privacy Issue. Artech House, London, UK, pp. 119\u2013134 <strong>2011<\/strong>.<\/p>\n<p>Mathe, J.L.; Nadas, A.; Sztipanovits, J. <a href=\"http:\/\/www.truststc.org\/pubs\/768.html\"><font color=\"#009922\">A Model-Integrated, Guideline-Driven, Clinical Decision-Support System<\/font><\/a>. Presented at the TRUST Review Meeting, Stanford, CA, USA <strong>2010<\/strong>.<\/p>\n<p>Hooper, M.H.; Martin, J.B.; Weavind, L.M.; Semler, M.W.; Albert, D.W.; Deane, N.B.; Paulett, J.M.; Mathe, J.L.; Miller, A.; Wheeler, A.P.; Bernard, G.R.; Rice, T.W. <a href=\"https:\/\/www.atsjournals.org\/doi\/abs\/10.1164\/ajrccm-conference.2010.181.1_MeetingAbstracts.A6137\"><font color=\"#009922\">Automated Surveillance Of Modified SIRS Criteria Is An Effective Tool For Detection Of Sepsis In The Medical Intensive Care Unit<\/font><\/a>, in: D53. SEPSIS: MECHANISMS AND IMPLICATIONS FOR MANAGEMENT, American Journal of Respiratory and Critical Care Medicine 2010. Presented at the American Thoracic Society 2010 International Conference, American Thoracic Society, New Orleans, pp. A6137\u2013A6137 <strong>2010<\/strong>.<\/p>\n<p>Mathe, J.L.; Martin, J.; Hooper, M. <a href=\"http:\/\/www.truststc.org\/pubs\/648.html\"><font color=\"#009922\">Towards an Adaptable Framework for Modeling, Verifying, and Executing Medical Guidelines<\/font><\/a>. Presented at the TRUST Review Meeting, Washington, D.C. <strong>2009a<\/strong>.<\/p>\n<p>Mathe, J.L. <font color=\"#009922\">Towards an Adaptable Framework for Modeling, Verifying, and Executing Medical Guidelines<\/font>, in: Proceedings of the Doctoral Symposium at MODELS 2009. Presented at the ACM\/IEEE 12th International Conference on Model Driven Engineering Languages and Systems (MODELS \u201909), Denver, CO <strong>2009<\/strong>.<\/p>\n<p>Mathe, J.L.; Martin, J.; Miller, P.; Ledeczi, A.; Weavind, L.; Nadas, A.; Miller, A.; Maron, D.; Sztipanovits, J. <font color=\"#009922\">A Model-Integrated, Guideline-Driven, Clinical Decision-Support System<\/font>. IEEE Softw. 26, 54\u201361 <strong>2009b<\/strong>.<\/p>\n<p>Mathe, J.L.; Martin, J.B.; Miller, P.; Ledeczi, A.; Weavind, L.; Miller, A.; Maron, D.J.; Nadas, A.; Sztipanovits, J. <font color=\"#009922\">STEEP &#8211; A Model-Integrated Clinical Information System Application<\/font>. Presented at the TRUST Review Meeting, Berkeley, CA <strong>2009c<\/strong>.<\/p>\n<p>Mathe, J.L.; Martin, J.; Miller, P.; Ledeczi, A.; Weavind, L.; Miller, A.; Maron, D.; Nadas, A.; Sztipanovits, J. <a href=\"http:\/\/www.truststc.org\/pubs\/529.html\"><font color=\"#009922\">STEEP &#8211; A Model-Integrated Clinical Information System Application<\/font><\/a>. Presented at the TRUST Review Meeting, Nashville, TN <strong>2008a<\/strong>.<\/p>\n<p>Mathe, J.L.; Martin, J.; Miller, P.; Weavind, L.; Maron, D.; Ledeczi, A.; Miller, A.; Nadas, A.; Sztipanovits, J. <a href=\"http:\/\/www.truststc.org\/pubs\/522.html\"><font color=\"#009922\">A Model-Integrated Approach to Implementing Individualized Patient Care Plans Based on Guideline-Driven Clinical Decision Support and Process Management<\/font><\/a>. Presented at the TRUST Review Meeting, Nashville, TN <strong>2008b<\/strong>.<\/p>\n<p>Martin, J.; Mathe, J.L.; Miller, P.; Ledeczi, A.; Weavind, L.; Miller, A.; Maron, D.J.; Nadas, A.; Sztipanovits, J. <font color=\"#009922\">A Model-Integrated Approach to Implementing Individualized Patient Care Plans Based on Guideline-Driven Clinical Decision Support and Process Management &#8211; A Progress Report<\/font>, in: 2nd International Workshop on Model-Based Design of Trustworthy Health Information Systems (MOTHIS 2008). Presented at the MOTHIS 2008 Workshop @ MODELS, Toulouse, France <strong>2008<\/strong>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Edited on 2018-08-21 &lt; Back to Publications Summary My work in clinical decision support has focused on two application areas of computer interpretable guidelines: plan-based and state-based (i.e. reactive) patient management systems. The later work focused on creating a prototype system for the detection and management of sepsis in a multiple intensive care unit (ICU)&#8230;<\/p>\n","protected":false},"author":2793,"featured_media":0,"parent":6,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"tags":[],"class_list":["post-187","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/my.vanderbilt.edu\/janosmathe\/wp-json\/wp\/v2\/pages\/187","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/my.vanderbilt.edu\/janosmathe\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/my.vanderbilt.edu\/janosmathe\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/janosmathe\/wp-json\/wp\/v2\/users\/2793"}],"replies":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/janosmathe\/wp-json\/wp\/v2\/comments?post=187"}],"version-history":[{"count":12,"href":"https:\/\/my.vanderbilt.edu\/janosmathe\/wp-json\/wp\/v2\/pages\/187\/revisions"}],"predecessor-version":[{"id":224,"href":"https:\/\/my.vanderbilt.edu\/janosmathe\/wp-json\/wp\/v2\/pages\/187\/revisions\/224"}],"up":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/janosmathe\/wp-json\/wp\/v2\/pages\/6"}],"wp:attachment":[{"href":"https:\/\/my.vanderbilt.edu\/janosmathe\/wp-json\/wp\/v2\/media?parent=187"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/janosmathe\/wp-json\/wp\/v2\/tags?post=187"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}