Publications

Peer-Reviewed Journal Papers
Clements LW, Collins JA, Weis JA, Simpson AL, Adams LB, Jarnagin WR, Miga MI. Evaluation of model-based deformation correction in image-guided liver surgery via tracked intraoperative ultrasound. Journal of Medical Imaging. 2016 Jan;3(1):015003.

Abramson, R.G., Arlinghaus, L., Dula, A., Quarles, C.C., Stokes, A., Weis, J.A. Whisenant, J., Williams, J., Chekmenev, E.Y., Zhukov, I., Yankeelov, T. MR Imaging Biomarkers in Oncology Clinical Trials. MRI Clinics of North America. 2016 Feb;24(1):11-29.

Conley, R.H., Meszoely, I.M., Weis, J.A., Pheiffer, T.S., Arlinghaus, L.R., Yankeelov, T.E., Miga, M.I. Realization of a biomechanical model-assisted image guidance system for breast cancer surgery using supine MRI. Int J Comput Assist Radiol Surg. 2015 Dec;10(12):1985-96.

Weis, J.A., Flint, K.M., Sanchez, V., Yankeelov, T.E., Miga, M.I. Assessing the accuracy and reproducibility of modality independent elastography in a murine model of breast cancer. Journal of Medical Imaging. 2015 Jul;2(3):036001.

Weis, J.A., Miga, M.I., Li, X., Arlinghaus, L.R., Abramson, V., Chakravarthy, A.B., Farley, J., Pendyala, P., Yankeelov, T.E. Predicting the Response of Breast Cancer to Neoadjuvant Chemotherapy Using a Mechanically Coupled Reaction-Diffusion Model. Cancer Research. 2015 Sep 2. pii: canres.2945.2014.

Hormuth, D., Weis, J.A., Barnes, S.L., Miga, M.I., Rericha, E., Quaranta, V., Yankeelov, T.E. Predicting in vivo glioma growth with the reaction diffusion equation constrained by quantitative magnetic resonance imaging data. Physical Biology. 2015 Jun 4;12(4):046006.

Felix, D.D., Gore, J.C., Yankeelov, T.E., Peterson, T.E., Barnes, S., Whisenant, J., Weis, J., Shoukouhi, S., Virostko, J., Nickels, M., McIntyre, J.O., Sanders, M., Abramson, V., Tantawy, M.N. Detection of breast cancer microcalcification using 99mTc-MDP SPECT or Osteosense 750EX FMT imaging. Nuclear Medicine and Biology. 2014 Mar;42(3):269-273.

Sun, K., Pheiffer T.S., Simpson, A.L., Weis, J.A., Dawant, B.M., Thompson, R.C., Miga, M.I. Near Real-time Computer Assisted Surgery for Brain Shift Correction using Biomechanical Models. IEEE Journal of Translational Engineering in Health and Medicine. 2014 Apr;2.

Weis, J.A., Miga, M.I., Arlinghaus, L.R., Li, X., Chakravarthy, A.B., Abramson, V., Farley, J., Yankeelov, T.E. A Mechanically Coupled Reaction-Diffusion Model for Predicting the Response of Breast Tumors to Neoadjuvant Chemotherapy. Physics in Medicine and Biology. 2013 Sept;58(17):5851-5866.

Yankeelov, T.E., Atuegwu, N., Hormuth, D., Weis, J.A., Barnes, S.L., Miga, M.I., Quaranta, V. Clinically Relevant Mathematical Modeling of Tumor Growth and Treatment Response. Science Translational Medicine. 2013 May;5(187):187ps9.

Abramson, R.G., Arlinghaus, L.R., Weis, J.A., Li, X., Dula, A.N., Chekmenev, E.Y., Smith, S.A., Miga, M.I., Abramson, V.G., Yankeelov, T.E. Current and emerging quantitative magnetic resonance imaging methods for assessing and predicting the response of breast cancer to neoadjuvant therapy. Breast Cancer: Targets and Therapy. 2012 Oct;2012(4):139-154. Review.

Simpson, A.L., Dumpuri, P., Ondrake, J.E., Weis, J.A., Jarnagin, W.R., Miga, M.I. Preliminary study of a novel method for conveying corrected image volumes in surgical navigation. Int J Med Robot. 2013 Mar;9(1):109-118.

Weis, V.G., Sousa, J.F., Lafleur, B.J., Nam, K.T., Weis, J.A., Finke, P.E., Ameen, N.A., Fox, J.G., Goldenring, J.R. Heterogeneity in mouse spasmolytic polypeptide-expressing metaplasia lineages identifies markers of metaplastic progression. Gut. 2013 Sep;62(9):1270-1279.

Weis, J.A., Granero-Molto, F., Myers, T.J., Longobardi, L., Spagnoli, A., Miga, M.I. Comparison of microCT and an inverse finite element approach for biomechanical analysis: Results in a MSC therapeutic system for fracture healing. J Biomech. 2012 Aug; 45(12):2164-2170

Myers, T.J., Yan, Y., Granero-Molto, F., Weis, J.A., Longobardi, L., Li, T., Li, Y., Contaldo, C., Ozkhan, H., Spagnoli, A. Systemically delivered insulin-like growth factor-I enhances mesenchymal stem cell-dependent fracture healing. Growth Factors. 2012 Aug; 30(4):230-241.

Granero-Molto, F., Myers, T.J., Weis, J.A., Longobardi, L., Li, T., Yan, Y., Case, N. Rubin, J., Spagnoli, A. Mesenchymal stem cells expressing insulin-like growth factor-I (MSCIGF) promote fracture healing and restore new bone formation in Irs1 knock-out mice: analyses of MSC IGF autocrine and paracrine regenerative effects. Stem Cells. 2011 Oct; 29(10):1537-1548.

Weis, J.A., Miga, M.I., Granero-Molto, F., Spagnoli, A. A finite element inverse analysis to assess functional improvement during the fracture healing process. J Biomech. 2010 Feb; 43(3):557-562.

Granero-Molto, F., Weis, J.A., Miga, M.I., Landis, B., Myers, T.J., O’Rear, L., Longobardi, L., Jansen E.D., Mortlock, D.P., Spagnoli, A.  Regenerative effects of transplanted mesenchymal stem cells in fracture healing.  Stem Cells. 2009 Aug; 27(8):1887-1898.

Granero-Molto, F., Weis, J.A., Longobardi, L., Spagnoli, A. Role of Mesenchymal Stem Cells in Regenerative Medicine: Application to Bone and Cartilage Repair. Expert Opinion on Biological Therapy. 2008 Mar; 8(3):255-268. Review.

Spagnoli, A., O’Rear, L., Chandler, R.L., Granero-Molto, F., Mortlock, D.P., Gorska, A.E., Weis, J.A., Longobardi, L., Chytil, A., Shimer, K., Moses, H.L. TGF-beta Signaling is Essential for Joint Morphogenesis. Journal of Cell Biology. 2007; 177: 1105-1117.

Conference Papers
Weis, J.A., Johnsen, A.M., Wile, G.E., Yankeelov, T.E., Abramson, R.G., Miga, M.I., Development of a diaphragmatic motion-based elastography framework for assessment of liver stiffness. SPIE 2015 Medical Imaging: Biomedical Applications in Molecular, Structural, and Functional Imaging.

Flint, K.M., Weis, J.A., Yankeelov, T.E., Miga, M.I., Repeatability assessment of modality independent elastography in a pre-clinical murine model. SPIE 2015 Medical Imaging: Biomedical Applications in Molecular, Structural, and Functional Imaging.

Weis, J.A., Kim, D.K., Yankeelov, T.E., Miga, M.I., Validation and reproducibility assessment of modality independent elastography in a pre-clinical model of breast cancer. SPIE 2014 Medical Imaging: Biomedical Applications in Molecular, Structural, and Functional Imaging.

Kim, D.K., Weis, J.A., Yankeelov, T.E., Miga, M.I.  Utilizing a reference material for assessing absolute tumor mechanical properties in modality independent elastography SPIE 2014 Medical Imaging: Biomedical Applications in Molecular, Structural, and Functional Imaging.

Weis, J.A., Yankeelov, T.E., Munoz, S.A., Sastry, R.A., Barnes, S.L., Arlinghaus, L.R., Li X., Miga, M.I. A consistent pre-clinical/clinical elastography approach for assessing tumor mechanical properties in therapeutic systems. SPIE 2013 Medical Imaging: Biomedical Applications in Molecular, Structural, and Functional Imaging.

Weis, J.A., Miga, M.I., Arlinghaus, L.R., Li, X., Chakravarthy, A.B., Abramson, V., Farley, J., Yankeelov, T.E. A mechanically coupled reaction diffusion model of breast tumor response during neoadjuvant chemotherapy. SPIE 2013 Medical Imaging: Biomedical Applications in Molecular, Structural, and Functional Imaging.

Miga, M.I., Dumpuri, P., Simpson, A.L., Weis, J.A., Jarnagin, W.R. The Sparse Data Extrapolation Problem: Strategies for Soft-Tissue Correction for Image-Guided Liver Surgery. SPIE 2011 Medical Imaging: Visualization, Image-Guided Procedures, and Modeling Conference, Vol. 7964, 2011.

Miga, M.I., Weis, J.A., Granero-Molto, F., and Spagnoli, A. Quantifying mechanical properties in a murine fracture healing system using inverse modeling: preliminary work. SPIE Medical Imaging 2010: Biomedical Applications in Molecular, Structural, and Functional Imaging, Vol.  7626, 2010.

Miga, M.I., Weis, J.A., Granero-Molto, F., and Spagnoli, A. Quantifying Mechanical Properties in a Murine Fracture Healing System Using an Inverse Geometric Nonlinear Elasticity Modeling Framework. 5th International Symposium on Biomedical Simulation, Lecture Notes in Computer Science, Vol. 5958, pp. 29-37, 2010.

Conference Abstracts (as primary author)
Weis, J.A., Miga, M.I., Arlinghaus, L.R., Li, X., Chakravarthy, A.B., Abramson, V., Farley, J., Yankeelov, T.E. Prediction of Response to Neoadjuvant Chemotherapy Using a Mechanical Coupled Reaction-Diffusion Model. AAPM 2014 Annual Meeting. Selected as Featured Presentation, Science Council Session: The Physics of Cancer.

Weis, J.A., Miga, M.I., Arlinghaus, L.R., Li, X., Chakravarthy, A.B., Abramson, V., Farley, J., Yankeelov, T.E. A Mechanically Coupled Reaction-Diffusion Model for Predicting the Response of Breast Cancer to Neoadjuvant Chemotherapy. ISMRM 2013 Annual Meeting.

Weis, J.A., Barnes, S.L., Yankeelov, T.E., and Miga, M.I. Material Property Assessment of a Murine Model of Triple Negative Breast Cancer Using Modality Independent Elastography: Preliminary Results. Biomedical Engineering Society Annual Meeting, Oct 2012.

Weis, J.A., Granero-Molto, F., Myers, T., Spagnoli, A., and Miga, M. An Inverse FEA to Assess Bone Fracture Healing in Mice Receiving Mesenchymal Stem Cell Transplantation. Biomedical Engineering Society Annual Meeting, Oct. 2010.

Weis, J. A., Granero-Molto, F., O’Rear, L. D., Miga, M. I. And Spagnoli, A. Development of a High-Resolution 3D Micro-CT Based Model to Predict Fracture Callus Histological Architecture. 29th Annual Meeting of American Society for Bone and Mineral Research, September 2007.