4/17/2020 Progress Report
- Background. The tumor microenvironment plays an important role in cancer growth and metastasis. Many aspects of cancer progression cannot be fully explained by two-dimensional representations of isolated components; they must be modeled in reference to the interactions of all the components and the product of these reactions. Current approaches to preclinical cancer research have significant disadvantages in replicating the complexity of the tumor microenvironment. To improve response to therapeutics, a more accurate preclinical model is needed that is translational to the three-dimensional human physiological system. Microfluidics, with its high-throughput capabilities, precise variable control, and ability to integrate with patient-derived cells, is one promising approach to an alternative preclinical model of the tumor environment for testing chemotherapeutics.
- Achievements since last report. Weekly team meetings have continued via Zoom. The market analysis and Design Day poster are completed. A copy of the poster was emailed to the Wikswo and Richmond lab for any suggested edits.
- Problems to address. We will refine the 4-5 minute presentation to ensure it is within the given time amount. In addition, we will make the appropriate changes if any are suggested by the Wikswo or Richmond lab.
- Future planned work. In the few days remaining before Senior Design Day on April 20th, we will continue rehearsing our presentation and prepping for our breakout meeting. Lastly, we are finishing turnover documents for the Wikswo and Richmond labs.