{"id":154,"date":"2019-03-19T15:54:45","date_gmt":"2019-03-19T20:54:45","guid":{"rendered":"http:\/\/my.vanderbilt.edu\/lopezlab\/?page_id=154"},"modified":"2021-08-12T07:39:34","modified_gmt":"2021-08-12T12:39:34","slug":"models","status":"publish","type":"page","link":"https:\/\/my.vanderbilt.edu\/lopezlab\/models\/","title":{"rendered":"Models"},"content":{"rendered":"

Models from the Lopez Lab<\/h1>\n

Extrinsic Apoptosis Reaction Model (EARM)<\/h2>\n

Publication:\u00a0Modeling a snap-action, variable-delay switch controlling extrinsic cell death<\/a>. (PLoS Biology, 2008)<\/p>\n

Github repository<\/a><\/p>\n

Documentation<\/a><\/p>\n

Contact: Lolab<\/a><\/p>\n

COX-2 Reaction Model (CORM)<\/h2>\n

Publication:\u00a0Competition and allostery govern substrate selectivity of cyclooxygenase-2<\/a>\u00a0(PNAS, 2015)<\/p>\n

Github repository<\/a><\/p>\n

Tutorial<\/a><\/p>\n

Contact: Lolab<\/a><\/p>\n

JNK3 Activation Reaction Model (JARM)<\/h2>\n

Publication:\u00a0Arrestin-3 scaffolding of the JNK3 cascade suggests a mechanism for signal amplification<\/a>. (PNAS, 2019)<\/p>\n

Github repository<\/a><\/p>\n

Contact: Lolab<\/a><\/p>\n

Apoptosis-Necrosis Reaction Model (ANRM)<\/h2>\n

Github repository<\/a><\/p>\n

Contact: Lolab<\/a><\/p>\n

NF-kB Model<\/h2>\n

Github repository<\/a><\/p>\n

Contact: Lolab<\/a><\/p>\n

EGFR Signaling Model<\/h2>\n

Github repository<\/a><\/p>\n

Contact: Lolab<\/a><\/p>\n

Division-Death Ratio Crosstalk Model (DDRXM)<\/h2>\n

Github repository<\/a><\/p>\n

Contact: Lolab<\/a><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Models from the Lopez Lab Extrinsic Apoptosis Reaction Model (EARM) Publication:\u00a0Modeling a snap-action, variable-delay switch controlling extrinsic cell death. (PLoS Biology, 2008) Github repository Documentation Contact: Lolab COX-2 Reaction Model (CORM) Publication:\u00a0Competition and allostery govern substrate selectivity of cyclooxygenase-2\u00a0(PNAS, 2015) Github repository Tutorial Contact: Lolab JNK3 Activation Reaction Model (JARM) Publication:\u00a0Arrestin-3 scaffolding of the JNK3…<\/p>\n","protected":false},"author":8228,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"tags":[],"class_list":["post-154","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/my.vanderbilt.edu\/lopezlab\/wp-json\/wp\/v2\/pages\/154","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/my.vanderbilt.edu\/lopezlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/my.vanderbilt.edu\/lopezlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/lopezlab\/wp-json\/wp\/v2\/users\/8228"}],"replies":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/lopezlab\/wp-json\/wp\/v2\/comments?post=154"}],"version-history":[{"count":3,"href":"https:\/\/my.vanderbilt.edu\/lopezlab\/wp-json\/wp\/v2\/pages\/154\/revisions"}],"predecessor-version":[{"id":183,"href":"https:\/\/my.vanderbilt.edu\/lopezlab\/wp-json\/wp\/v2\/pages\/154\/revisions\/183"}],"wp:attachment":[{"href":"https:\/\/my.vanderbilt.edu\/lopezlab\/wp-json\/wp\/v2\/media?parent=154"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/lopezlab\/wp-json\/wp\/v2\/tags?post=154"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}