{"id":4,"date":"2012-09-06T23:28:35","date_gmt":"2012-09-06T23:28:35","guid":{"rendered":"https:\/\/my.vanderbilt.edu\/lopezlab\/about-me\/"},"modified":"2021-08-12T14:01:45","modified_gmt":"2021-08-12T19:01:45","slug":"about-me","status":"publish","type":"page","link":"https:\/\/my.vanderbilt.edu\/lopezlab\/about-me\/","title":{"rendered":"Lab Members"},"content":{"rendered":"<p><strong><span style=\"text-decoration: underline\">Carlos F. Lopez Ph. D.:<\/span><\/strong> My formal training has been in the fields of chemistry, physics, biophysics, biochemistry, and molecular cell biology with a unique emphasis on the development and application of modeling techniques. I apply my skill-set\u00a0in cell molecular and systems biology with a focus in cancer research. Given my training from atomic interactions to continuum-cellular interactions I am deeply interested in how events that take place at one space-time scale (e.g. quantum interactions) have an effect on the interactions at the macroscale. From this perspective, cancer biology is a perfect area of application to my theoretical interests due to its inherent multi-scale properties. At the same time, I believe a thorough understanding of cancer development and progression necessitates the development of a multi-scale theoretical foundation that can account for events such as DNA\/genomic level aberrations (atomic space and time scales), protein malfunctions, and others, and their propagation to proteins (molecular scales), organelles, cells, and ultimately organs. My driving hypothesis is that understanding the events involved in cancer at multiple scales and developing theories and models to explore cancer biology from systems perspective are key to developing novel successful cancer treatments. This goal is quite ambitious, and I am approaching it by initially focusing on cell signaling pathways that exhibit dysregulation in cancer phenotypes. I also work on trying to provide a novel theoretical understanding of cancer progression that, in turn, will open new possibilities for targeted treatments.<\/p>\n<p><span style=\"text-decoration: underline\"><strong>Staff (General interests):<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"text-decoration: underline\">Jonathan Lifferth<\/span> :\u00a0Research Analyst (MS Pharmacology) :\u00a0Tracking hepatocellular cancer cell movement<\/li>\n<li><span style=\"text-decoration: underline\">Yukthi Papanna Suresh<\/span> : Software Developer (MS Computer Science) : Scientific software for numerical computing, software vulnerability analysis, web-based dissemination and visualization.<\/li>\n<\/ul>\n<p><span style=\"text-decoration: underline\"><strong>Graduate Students (Program: General interests):<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"text-decoration: underline\">Michael Irvin<\/span> (Interdisciplinary, Sys Bio &amp; Stats): Machine learning, signaling crosstalk, model calibration and analysis.<\/li>\n<li><span style=\"text-decoration: underline\">Samantha Beik<\/span> (Medical Sciences Training Program): Cell identity, cell growth dynamics, cell response to\u00a0perturbations.<\/li>\n<li><span style=\"text-decoration: underline\">Bryan Glazer<\/span> (Biomedical Informatics): Network modeling, machine learning, information theory.<\/li>\n<li><span style=\"text-decoration: underline\">Perry Wasdin<\/span> (Chemical and Physical Biology) :\u00a0Network analysis, machine learning, information theory.<\/li>\n<li><span style=\"text-decoration: underline\">Rebecca Creed<\/span> (Mechanical Engineering) :\u00a0Information Theory, Complex Systems<\/li>\n<li><span style=\"text-decoration: underline\">Mafe Senosain<\/span>\u00a0(Cancer Biology) : Computational biology, bioinformatics, data analysis.<\/li>\n<\/ul>\n<p><span style=\"text-decoration: underline\"><strong>Postdoctoral Fellows\u00a0(General interests):<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"text-decoration: underline\">Alexander Lubbock<\/span>, PhD: Modeling infrastructure and dynamic cellular processes with single-cell resolution.<\/li>\n<li><a href=\"https:\/\/my.vanderbilt.edu\/mustafaozen\/\"><span style=\"text-decoration: underline\">Mustafa Ozen<\/span><\/a>, PhD:\u00a0Computational Systems Biology, Machine Learning, Optimization.<\/li>\n<li><span style=\"text-decoration: underline\">Federico Fontana<\/span>, PhD: Computational chemistry and Theoretical Chemistry with several applications in the field of materiomics, nanomedicine and biology.<\/li>\n<li><span style=\"text-decoration: underline\">Martina Prugger<\/span>, PhD: Numerical algorithms, scientific computing, high performance computing, and biological applications.<\/li>\n<li><span style=\"text-decoration: underline\">James Pino<\/span>, PhD: Multi-omics analysis, data mining, automated model generation, stochastic simulation methods, GPU programming.<\/li>\n<\/ul>\n<p><span style=\"text-decoration: underline\"><strong>Rotation Students:<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"text-decoration: underline\">Liane V\u00e1squez-Weber<\/span> :\u00a0Summer Intern (Texas Tech University, Computer Science and Biology)<\/li>\n<\/ul>\n<p><span style=\"text-decoration: underline\"><strong>Visiting\u00a0(General interests):<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"text-decoration: underline\">Naotoshi Nakamura<\/span>, PhD, Associate Professor at Osaka University: Cell response to drug treatment, signaling models.<\/li>\n<\/ul>\n<p><span style=\"text-decoration: underline\"><strong>Alumni:<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"text-decoration: underline\">Oscar Ortega<\/span>. PhD | Vanderbilt,\u00a0Quantitative and Chemical Biology<\/li>\n<li><span style=\"text-decoration: underline\">Shawn Garbett<\/span>, MS | Vanderbilt U, Assistant in Biostatistics<\/li>\n<li><span style=\"text-decoration: underline\">Erin Shockley<\/span>, PhD | Data Scientist, Ascension<\/li>\n<li><span style=\"text-decoration: underline\">Leonard Harris<\/span>, PhD | Asst. Professor at U of Arkansas, Dept. of Biomedical Engineering<\/li>\n<li><span style=\"text-decoration: underline\">Blake Wilson<\/span>, PhD | Research Associate at U of Texas at Dallas, Dept. of Bioengineerin<\/li>\n<li><span style=\"text-decoration: underline\">Michael Kochen<\/span> PhD | Postdoc at U of Washington at Seattle, Dept of Bioengineering<\/li>\n<li><span style=\"text-decoration: underline\">Melaine Sebastian<\/span> |\u00a0SCLC cell identity. Forever in our hearts.<\/li>\n<li><span style=\"text-decoration: underline\">Geena Ildefonso <\/span>PhD | Vanderbilt, Chemical and Physical Biology<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Carlos F. Lopez Ph. D.: My formal training has been in the fields of chemistry, physics, biophysics, biochemistry, and molecular cell biology with a unique emphasis on the development and application of modeling techniques. I apply my skill-set\u00a0in cell molecular and systems biology with a focus in cancer research. Given my training from atomic interactions&#8230;<\/p>\n","protected":false},"author":995,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"footnotes":""},"tags":[],"class_list":["post-4","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/my.vanderbilt.edu\/lopezlab\/wp-json\/wp\/v2\/pages\/4","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/my.vanderbilt.edu\/lopezlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/my.vanderbilt.edu\/lopezlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/lopezlab\/wp-json\/wp\/v2\/users\/995"}],"replies":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/lopezlab\/wp-json\/wp\/v2\/comments?post=4"}],"version-history":[{"count":32,"href":"https:\/\/my.vanderbilt.edu\/lopezlab\/wp-json\/wp\/v2\/pages\/4\/revisions"}],"predecessor-version":[{"id":187,"href":"https:\/\/my.vanderbilt.edu\/lopezlab\/wp-json\/wp\/v2\/pages\/4\/revisions\/187"}],"wp:attachment":[{"href":"https:\/\/my.vanderbilt.edu\/lopezlab\/wp-json\/wp\/v2\/media?parent=4"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/lopezlab\/wp-json\/wp\/v2\/tags?post=4"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}