{"id":534,"date":"2016-02-27T14:53:12","date_gmt":"2016-02-27T19:53:12","guid":{"rendered":"https:\/\/my.vanderbilt.edu\/masi\/?p=534"},"modified":"2016-11-01T12:29:40","modified_gmt":"2016-11-01T17:29:40","slug":"a-3d-high-resolution-ex-vivo-white-matter-atlas-of-the-common-squirrel-monkey-saimiri-sciureus-based-on-diffusion-tensor-imaging","status":"publish","type":"post","link":"https:\/\/my.vanderbilt.edu\/masi\/2016\/02\/a-3d-high-resolution-ex-vivo-white-matter-atlas-of-the-common-squirrel-monkey-saimiri-sciureus-based-on-diffusion-tensor-imaging\/","title":{"rendered":"A 3D high resolution ex vivo white matter atlas of the common squirrel monkey (Saimiri sciureus) based on diffusion tensor imaging."},"content":{"rendered":"
Yurui Gao, Prasanna Parvathaneni, Kurt G. Schilling, Zhoubing Xu, Ann S. Choe, Bennett A. Landman, Adam M. Anderson. A 3D high resolution ex vivo white matter atlas of the common squirrel monkey (Saimiri sciureus) based on diffusion tensor imaging. In Proceedings of the SPIE Medical Imaging Conference. San Diego, California, February 2016.<\/p>\n
Full Text<\/strong><\/h2>\n
Abstract<\/strong><\/h2>\n
Modern magnetic resonance imaging<\/span> (MRI) brain atlases are high<\/span> quality 3-D volumes with specific structures labeled in the volume. Atlases are essential in providing a common<\/span> space for interpretation of results across studies, for anatomical education, and providing quantitative image-based<\/span> navigation. Extensive work has been devoted to atlas<\/span> construction for humans, macaque, and several non-primate species (e.g., rat). One notable gap in the literature is the common<\/span> squirrel<\/span> monkey<\/span> – for which the primary published atlases date from the 1960’s. The common<\/span> squirrel<\/span> monkey<\/span> has been used extensively as surrogate for humans in biomedical studies, given its anatomical neuro-system similarities and practical considerations. This work describes the continued development of a multi-modal MRI atlas<\/span> for the common<\/span> squirrel<\/span> monkey<\/span>, for which a structural imaging<\/span> space and gray matter<\/span> parcels have been previously constructed. This study adds white<\/span> matter<\/span> tracts to the atlas<\/span>. The new atlas<\/span> includes 49 white<\/span> matter<\/span> (WM) tracts, defined using diffusion<\/span> tensor<\/span> imaging<\/span> (DTI) in three animals and combines these data to define the anatomical locations of these tracks in a standardized coordinate system compatible with previous development. An anatomist reviewed the resulting tracts and the inter-animal reproducibility (i.e., the Dice index of each WM parcel across animals in common<\/span> space) was assessed. The Dice indices range from 0.05 to 0.80 due to differences of local registration quality and the variation of WM tract position across individuals. However, the combined WM labels from the 3 animals represent the general locations of WM parcels, adding basic connectivity information to the atlas<\/span>.<\/p>\nFigure 2 The pipeline for iterative definition of one bundle \u2013 the left cingulum in native space of one monkey.<\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"
Yurui Gao, Prasanna Parvathaneni, Kurt G. Schilling, Zhoubing Xu, Ann S. Choe, Bennett A. Landman, Adam M. Anderson. A 3D high resolution ex vivo white matter atlas of the common squirrel monkey (Saimiri sciureus) based on diffusion tensor imaging. In Proceedings of the SPIE Medical Imaging Conference. San Diego, California, February 2016. Full Text Abstract…<\/p>\n","protected":false},"author":6300,"featured_media":535,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[33,3,4],"tags":[72,17],"class_list":["post-534","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-diffusion-tensor-imaging","category-image-segmentation","category-neuroimaging","tag-saimiri-sciureus","tag-white-matter"],"_links":{"self":[{"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/posts\/534","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/users\/6300"}],"replies":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/comments?post=534"}],"version-history":[{"count":1,"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/posts\/534\/revisions"}],"predecessor-version":[{"id":536,"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/posts\/534\/revisions\/536"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/media\/535"}],"wp:attachment":[{"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/media?parent=534"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/categories?post=534"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/tags?post=534"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
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