{"id":606,"date":"2016-09-01T12:33:24","date_gmt":"2016-09-01T17:33:24","guid":{"rendered":"https:\/\/my.vanderbilt.edu\/masi\/?p=606"},"modified":"2016-11-03T09:35:44","modified_gmt":"2016-11-03T14:35:44","slug":"can-we-get-around-the-crossing-fiber-problem-by-increasing-spatial-resolution","status":"publish","type":"post","link":"https:\/\/my.vanderbilt.edu\/masi\/2016\/09\/can-we-get-around-the-crossing-fiber-problem-by-increasing-spatial-resolution\/","title":{"rendered":"Can We Get Around the Crossing Fiber Problem by Increasing Spatial resolution?"},"content":{"rendered":"<p>Kurt G. Schilling, Vaibhav Janve, Yurui Gao, Iwona Stepniewska, Bennett A. Landman, Adam W Anderson. \u201cCan We Get Around the Crossing Fiber Problem by Increasing Spatial resolution?\u201d In Proceedings of the ISMRM Workshop on Diffusion MRI. Lisbon, Portugal, September 2016. Oral presentation.<\/p>\n<p><strong>Full text:<\/strong> <a href=\"https:\/\/my.vanderbilt.edu\/masi\/wp-content\/uploads\/sites\/2304\n2661\/2016\/09\/crossing_vs_resolution_abstract_v2.pdf\">PDF<\/a><\/p>\n<h2>Abstract<\/h2>\n<p>It is now widely recognized that voxels with crossing fibers and complex configurations present a\u00a0challenge for diffusion MRI (dMRI) reconstruction and fiber tracking algorithms. This \u201ccrossing fiber\u201d problem\u00a0has been estimated to affect anywhere from 30% [1] to 90% [2] of white matter (WM) voxels, and it is generally\u00a0assumed that increasing the spatial resolution as much as possible will minimize the number of voxels containing\u00a0multiple fiber populations. Here, using both dMRI and histology from the\u00a0same brain, we investigate the\u00a0prevalence of this crossing fiber problem across a range of spatial resolutions.<\/p>\n<figure id=\"attachment_826\" aria-describedby=\"caption-attachment-826\" style=\"width: 500px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-826\" src=\"https:\/\/my.vanderbilt.edu\/masi\/wp-content\/uploads\/sites\/2304\n2661\/2016\/09\/crossing_vs_resolution_abstract_v2.jpg\" alt=\"Figure 1 shows the results of ST analysis in a region with in-plane fiber crossings. We find that, in both MRI and histology, the percent of voxels with crossing fibers actually increases as we increase the resolution. The middle and bottom rows highlight \u201csingle\u201d fiber regions in red and \u201ccrossing\u201d fibers as green, and qualitatively show that many regions with a \u201csingle\u201d fiber population at a coarse resolution exhibit crossing patterns when processed at a finer resolution.\" width=\"500\" height=\"244\" \/><figcaption id=\"caption-attachment-826\" class=\"wp-caption-text\">Figure 1 shows the results of ST analysis in a region with in-plane fiber crossings. We find that, in both MRI and histology, the percent of voxels with crossing fibers actually increases as we increase the resolution. The\u00a0middle and bottom rows highlight \u201csingle\u201d fiber regions in red and \u201ccrossing\u201d fibers as green, and qualitatively\u00a0show that many regions with a \u201csingle\u201d fiber population at a coarse resolution exhibit crossing patterns when\u00a0processed at a finer resolution.<\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Kurt G. Schilling, Vaibhav Janve, Yurui Gao, Iwona Stepniewska, Bennett A. Landman, Adam W Anderson. \u201cCan We Get Around the Crossing Fiber Problem by Increasing Spatial resolution?\u201d In Proceedings of the ISMRM Workshop on Diffusion MRI. Lisbon, Portugal, September 2016. Oral presentation. Full text: PDF Abstract It is now widely recognized that voxels with crossing&#8230;<\/p>\n","protected":false},"author":6322,"featured_media":826,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[124,33,9],"tags":[],"class_list":["post-606","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-crossing-fibers","category-diffusion-tensor-imaging","category-diffusion-weighted-mri"],"_links":{"self":[{"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/posts\/606","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/users\/6322"}],"replies":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/comments?post=606"}],"version-history":[{"count":6,"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/posts\/606\/revisions"}],"predecessor-version":[{"id":830,"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/posts\/606\/revisions\/830"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/media\/826"}],"wp:attachment":[{"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/media?parent=606"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/categories?post=606"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/my.vanderbilt.edu\/masi\/wp-json\/wp\/v2\/tags?post=606"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}