Bile Acid may Reduce Psychedelic effects of Cocaine

Research conducted at Vanderbilt University has shown that an increase in the hormone Bile Acid can decrease the hallucinations due to cocaine.

A previous study conducted in mice found that an increase in the levels of the Bile Acid in the  bloodstream decreases rewards associated with high fat foods. As a result, a surgery to increase Bile Acid levels in mice was developed. Charles Flyn, a professor of surgery, and his fellow researchers used this surgery on mice before giving them cocaine. They found that like the fatty foods, the hormone decreased the hallucinations, and therefore, the reward associated with cocaine. The findings are especially useful for further research that could aim to help cocaine addicts overcome their addiction.

 

The full Journal is Published in PLOS Biology.


Doi: https://doi.org/10.1371/journal.pbio.2006682

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