Daily Archives: April 25, 2015

LRIG1 Regulates Ontogeny of Smooth Muscle−Derived Subsets of Interstitial Cells of Cajal in Mice

Posted on April 25, 2015 by Jumpei Kondo, Anne E. Powell, Yang Wang, Melissa A. Musser, E. Michelle Southard-Smith, Jeffrey L. Franklin, Robert J. Coffey

Interstitial cells of Cajal (ICC) control intestinal smooth muscle contraction to regulate gut motility. ICC within the plane of the myenteric plexus (ICC-MY) arise from KIT-positive progenitor cells during mouse embryogenesis. However, little is known… Continue reading →

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Effect of Amitriptyline and Escitalopram on Functional Dyspepsia: A Multicenter, Randomized Controlled Study

Posted on April 25, 2015 by Nicholas J. Talley, G. Richard Locke, Yuri A. Saito, Ann E. Almazar, Ernest P. Bouras, Colin W. Howden, Brian E. Lacy, John K. DiBaise, Charlene M. Prather, Bincy P. Abraham, Hashem B. El-Serag, Paul Moayyedi, Linda M. Herrick, Lawrence A. Szarka, Mi

Antidepressants are frequently prescribed to treat functional dyspepsia (FD), a common disorder characterized by upper abdominal symptoms, including discomfort or postprandial fullness. However, there is little evidence of the efficacy of these drugs i… Continue reading →

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