Daily Archives: April 29, 2015

Combining Data From Liver Disease Scoring Systems Better Predicts Outcomes of Patients With Alcoholic Hepatitis

Posted on April 29, 2015 by Alexandre Louvet, Julien Labreuche, Florent Artru, Jérôme Boursier, Dong Joon Kim, John O’Grady, Eric Trépo, Pierre Nahon, Nathalie Ganne-Carrié, Sylvie Naveau, Emmanuel Diaz, Thierry Gustot, Guillaume Lassailly, Amélie Cannesson-Leroy, Valérie Canva

Several models have been used to determine prognoses of patients with alcoholic hepatitis. These include static systems (the Maddrey discriminant function; age, bilirubin, international normalized ratio, creatinine [ABIC] score; and model for end-stage… Continue reading →

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An Accurate Cancer Incidence in Barrett’s Esophagus: A Best Estimate Using Published Data and Modeling

Posted on April 29, 2015 by S. Kroep, I. Lansdorp-Vogelaar, J.H. Rubenstein, H.J. de Koning, R. Meester, J.M. Inadomi, M. van Ballegooijen

Published estimates for the rate of progression from Barrett’s esophagus (BE) to esophageal adenocarcinoma (EAC) vary. We used simulation modeling to reconcile published data and more accurately estimate the incidence of EAC among people with BE. Continue reading →

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Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease

Posted on April 29, 2015 by Paul Angulo, David E. Kleiner, Sanne Dam-Larsen, Leon A. Adams, Einar S. Bjornsson, Phunchai Charatcharoenwitthaya, Peter R. Mills, Jill C. Keach, Heather D. Lafferty, Alisha Stahler, Svanhildur Haflidadottir, Flemming Bendtsen

Histologic analysis of liver biopsy specimens allows for grading and staging of nonalcoholic fatty liver disease (NAFLD). We performed a longitudinal study to investigate the long-term prognostic relevance of histologic features for patients with NAFLD. Continue reading →

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