Daily Archives: May 27, 2015

Association Between Plasma Levels of Macrophage Inhibitory Cytokine-1 Before Diagnosis of Colorectal Cancer and Mortality

Posted on May 27, 2015 by Raaj S. Mehta, Dawn Q. Chong, Mingyang Song, Jeffrey A. Meyerhardt, Kimmie Ng, Reiko Nishihara, Zhirong Qian, Teppei Morikawa, Kana Wu, Edward L. Giovannucci, Charles S. Fuchs, Shuji Ogino, Andrew T. Chan

Patients with colorectal cancer (CRC) have high circulating levels of macrophage inhibitory cytokine-1 (MIC1 or growth differentiation factor 15), a marker of inflammation that might be involved in carcinogenesis. We analyzed blood samples collected fr… Continue reading →

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High Prevalence of Nonalcoholic Fatty Liver Disease in Adolescents Undergoing Bariatric Surgery

Posted on May 27, 2015 by Stavra A. Xanthakos, Todd M. Jenkins, David E. Kleiner, Tawny W. Boyce, Reena Mourya, Rebekah Karns, Mary L. Brandt, Carroll M. Harmon, Michael A. Helmrath, Marc P. Michalsky, Anita P. Courcoulas, Meg H. Zeller, Thomas H. Inge, Teen-LABS Consortium

Little is known about the prevalence of nonalcoholic fatty liver disease (NAFLD) among severely obese adolescents or factors that determine its development. We investigated the prevalence of NAFLD in a multicenter cohort of adolescents undergoing baria… Continue reading →

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High Proportions of People With Nonceliac Wheat Sensitivity Have Autoimmune Disease or Antinuclear Antibodies

Posted on May 27, 2015 by Antonio Carroccio, Alberto D’Alcamo, Francesca Cavataio, Maurizio Soresi, Aurelio Seidita, Carmelo Sciumè, Girolamo Geraci, Giuseppe Iacono, Pasquale Mansueto

There is much interest in wheat sensitivity among people without celiac disease (CD), but little is known about any risks associated with the condition. We evaluated the prevalence of autoimmune diseases (ADs) among patients with nonceliac wheat sensit… Continue reading →

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KIT Signaling Promotes Growth of Colon Xenograft Tumors in Mice and Is Up-Regulated in a Subset of Human Colon Cancers

Posted on May 27, 2015 by Evan C. Chen, Taylor A. Karl, Tomer Kalisky, Santosh K. Gupta, Catherine A. O’Brien, Teri A. Longacre, Matt van de Rijn, Stephen R. Quake, Michael F. Clarke, Michael E. Rothenberg

Receptor tyrosine kinase (RTK) inhibitors have advanced colon cancer treatment. We investigated the role of the RTK KIT in development of human colon cancer. Continue reading →

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