An Unusual Cause of a Pancreatic Mass

Question: An 88-year-old man with a past medical history of melanoma presented for evaluation of a pancreatic tail mass found on routine imaging follow-up of a stable lung nodule (Figure A). He was asymptomatic and his physical examination revealed no lymphadenopathy, jaundice, or abdominal masses. Laboratory examination demonstrated a carbohydrate antigen (CA)19-9 level of 14 U/mL (normal, 0-40). Endoscopic ultrasonography (EUS) demonstrated a 1.9 × 0.9-cm hypoechoic pancreatic tail lesion with irregular margins (Figure B).

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