Written as part of the Differential Diagnoses in Surgical Pathology series, this text greatly fulfills Montgomery and Greens’ hopes to “offer fresh information to trainees and help solidify fine points for more experienced pathologists [in gastrointestinal pathology].” They achieve this by covering common diagnostic dilemmas, including grading dysplasia in Barrett esophagus or distinguishing colitis-associated dysplasia from reactive changes. Differential diagnoses of rarer entities, for example, tufting enteropathy and microvillous inclusion disease that, as a result of being seen infrequently, are unfamiliar to many pathologists, are also covered.