Monthly Archives: June 2015

We read with great interest the article by Hirschfield et al,1 who evaluated the efficacy and safety of obeticholic acid (OCA) in a randomized, controlled trial of patients with primary biliary cirrhosis (PBC) who had exhibited an inadequate response … Continue reading →

Our analysis was based on a longitudinal follow-up cohort and excluded prevalent lesions to establish the temporal relationship between irritable bowel syndrome (IBS) and colorectal cancer (CRC). Therefore, our implication based on the finding can be b… Continue reading →

We are grateful to Drs Aghemo and Colombo for the concise summary of our recent paper, and read with great interest their insightful comment that deals with the implications from our study, which demonstrated extrahepatic effectiveness of interferon (… Continue reading →

The stated mission of the Practice & Quality Department of the American Gastroenterological Association Institute (AGA) is to help gastroenterologists provide high-quality, high-value care by contributing to the definition of optimal clinical practice. The publication of evidence-based clinical guidelines is essential to achieving this overarching goal. Over the past five years, the range of clinical guidance products offered by the AGA has grown in size while improving in quality. Every new AGA guideline provides focused, actionable clinical recommendations based on in-depth systematic reviews of available evidence. Continue reading →

Hepatitis B (HBV) is a virus that affects the liver. Not everyone with HBV will have symptoms when they are infected. HBV will usually go away on its own within 6 months, but sometimes it becomes a long-term (chronic) infection. The DNA of the virus ca… Continue reading →

Pancreatic cysts are small sacs of fluid that grow on or inside the pancreas. Most pancreatic cysts are harmless and only need a series of three MRI scans to rule out any risks to your health. Less often, a cyst may require an endoscopic procedure call… Continue reading →

This paperback manual is a condensed version of the full textbook, The ASCRS Textbook of Colon and Rectal Surgery, 2nd edition. The editors sought to provide a daily, portable reference for medical students, residents, fellows, primary care providers, … Continue reading →

The Manual of Nutritional Therapeutics is designed to provide information of a practical nature for health professionals and students. It is clearly focused on the needs of clinicians rather than being a general textbook of nutrition. Continue reading →

Since the publication of its first edition in 1973, Sleisenger and Fordtran (S&F) has remained the standard reference against which every other general textbook in digestive diseases must be compared. Now in its 10th edition, S&F remains true to form, … Continue reading →

Many thanks to Dong et al for their correspondence regarding our phase II randomized, controlled trial (NCT00550862) of obeticholic acid (OCA) in primary biliary cirrhosis (PBC).1 Notably, we were able to demonstrate biochemical efficacy of OCA in pat… Continue reading →