Daily Archives: June 8, 2015

Interleukin-8 Induces Expression of FOXC1 to Promote Transactivation of and in Hepatocellular Carcinoma Cell Lines and Formation of Metastases in Mice

Posted on June 8, 2015 by Wenjie Huang, Zhangqian Chen, Lin Zhang, Dean Tian, Daowen Wang, Daiming Fan, Kaichun Wu, Limin Xia

Inflammation regulated by interleukin (IL) 8 promotes metastasis of hepatocellular carcinoma (HCC). The transcription factor forkhead box C1 (FOXC1) promotes metastasis by activating the epithelial to mesenchymal transition; its levels in liver tumors … Continue reading →

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