Daily Archives: June 26, 2015

Abdominal Distension in a Patient With Hepatocellular Carcinoma

Question: A 71-year-old man with chronic hepatitis B-related liver cirrhosis and hepatocellular carcinoma was brought to the emergency department because he had experienced progressive abdominal distension for 1 week. The hepatoma had recently progress… Continue reading

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An Unusual Cause of Anterior Abdominal Wall Abscess

Question: A 71-year-old woman, who had no previous psychiatric history or abdominal surgery, was admitted to the hospital for left hypochondrial mass for 2 weeks, associated with an ache over the area and loss of appetite for the same duration. No feve… Continue reading

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Leg Swelling and Mildly Deranged Liver Tests: An Unusual Presentation of a Usual Diagnosis

Question: A 72-year-old woman presented to the hospital with progressively worsening left lower extremity swelling and pain of 1 weeks’ duration. She also reported vague right upper abdominal discomfort, but did not complain of nausea, vomiting, shor… Continue reading

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Esophageal Ulcer in a Lung Cancer Patient

Question: A 69-year-old Japanese woman with persistent cough visited our hospital. She was diagnosed with unresectable non-small cell lung cancer (adenocarcinoma) by histologic examination of biopsied samples during bronchoscopy. The patient was treate… Continue reading

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Reflections on Mentorship on the Occasion of Dr Kurt J. Isselbacher’s 90th Birthday

It seems that until relatively recently, mentorship was hardly a topic of comment in academic discourse. Without doubt, the historical neglect of the role of mentors as appropriate for explicit discussion was a significant omission. However, within a … Continue reading

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Physician Non-adherence to Colonoscopy Interval Guidelines in the Veterans Affairs Healthcare System

Colonoscopy can decrease colorectal cancer (CRC) mortality, although performing this procedure more frequently than recommended could increase costs and risks to patients. We aimed to determine rates and correlates of physician non-adherence to guideli… Continue reading

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Exome Sequencing Reveals Germline Mutation that Reduces PTEN Expression and is Associated with Hamartomatous Polyposis and Gastrointestinal Ganglioneuromas

Hamartomatous polyposis syndromes (HPS) account for a small but appreciable proportion of inherited gastrointestinal cancer predisposition syndromes; patients with HPS have an increased risk for colon and extracolonic malignancies. We present a unique … Continue reading

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A Rare Cause of Abdominal Pain by Pancreatic Mass in a Young Female Patient

Question: A 24-year-old woman presented with epigastric pain which began about 2 years ago and progressively worsened over the past 6 months. The pain occurred intermittently but usually began after a meal, lasted for about 1 hour, and radiated to the… Continue reading

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Covering the Cover

The treatment of severe acute pancreatitis remains largely supportive because pharmacotherapy that affects the clinical course has yet to be realized. The consequences of severe acute pancreatitis that contributes to increase morbidity and mortality in… Continue reading

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