Daily Archives: July 8, 2015

Proton Pump Inhibitors Alter Specific Taxa in the Human Gastrointestinal Microbiome: A Crossover Trial

Posted on July 8, 2015 by Daniel E. Freedberg, Nora C. Toussaint, Sway P. Chen, Adam J. Ratner, Susan Whittier, Timothy C. Wang, Harris H. Wang, Julian A. Abrams

We conducted an open-label crossover trial to test whether proton pump inhibitors (PPIs) affect the gastrointestinal microbiome to facilitate Clostridium difficile infection (CDI). Twelve healthy volunteers each donated 2 baseline fecal samples, 4 week… Continue reading →

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Genetics, Genetic Testing and Management of Hemochromatosis: 15 years since hepcidin

Posted on July 8, 2015 by Antonello Pietrangelo

The discovery of hepcidin in 2000 and the subsequent unprecedented explosion of research and discoveries in the iron field have dramatically changed our understanding of human disorders of iron metabolism. Today, hereditary hemochromatosis, the paradig… Continue reading →

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Longer Withdrawal Time Is Associated With a Reduced Incidence of Interval Cancer After Screening Colonoscopy

Posted on July 8, 2015 by

Withdrawal times and adenoma detection rates are widely used quality indicators for screening colonoscopy. More rapid withdrawal times have been associated with undetected adenomas, which can increase risk for interval colorectal cancer. Continue reading →

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