Daily Archives: July 28, 2015

Covering the Cover

In contrast with celiac disease, (CD) which is characterized by an immune-based reaction to gluten, primarily involving the small intestine, in genetically predisposed individuals, nonceliac gluten sensitivity or, more accurately, nonceliac wheat sensi… Continue reading

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Digital Health: Hope, Hype, and Amara’s Law

We live in the digital age. Digital technology is changing all aspects of our lives, including how we work and spend our leisure time, how we relate to others, and even how we think. Although late compared with other industries, digital technologies ar… Continue reading

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Digital Health: Hope, Hype, and Amara’s Law

We live in the digital age. Digital technology is changing all aspects of our lives, including how we work and spend our leisure time, how we relate to others, and even how we think. Although late compared with other industries, digital technologies ar… Continue reading

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Next Generation Multigene Panel Testing: The Next step for identification of Hereditary Colorectal Cancer Syndromes?

This issue of Gastroenterology presents a manuscript by Yurgelun et al1 that addresses the question of whether multigene panel testing offers “meaningful advantages over targeted criteria-based genetic testing” in patients meeting criteria for the… Continue reading

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Next Generation Multigene Panel Testing: The Next step for identification of Hereditary Colorectal Cancer Syndromes?

This issue of Gastroenterology presents a manuscript by Yurgelun et al1 that addresses the question of whether multigene panel testing offers “meaningful advantages over targeted criteria-based genetic testing” in patients meeting criteria for the… Continue reading

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Trials and Tribulations: The Prevention of Variceal Rebleeding

The last 25 years of portal hypertension clinical research has directly resulted in a reduction in variceal bleeding mortality from 50% to 20%. This research has included introduction of new techniques, technological refinements, and application of old… Continue reading

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Trials and Tribulations: The Prevention of Variceal Rebleeding

The last 25 years of portal hypertension clinical research has directly resulted in a reduction in variceal bleeding mortality from 50% to 20%. This research has included introduction of new techniques, technological refinements, and application of old… Continue reading

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c-Kit as a Novel Potential Therapeutic Target in Colorectal Cancer

Studies to identify the cells that fuel colorectal cancer (CRC) cell renewal and metastasis have shown that such behavior is enriched in a subpopulation of cells with stem cell-like features or tumor-initiating cells. The identification of drugs that t… Continue reading

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c-Kit as a Novel Potential Therapeutic Target in Colorectal Cancer

Studies to identify the cells that fuel colorectal cancer (CRC) cell renewal and metastasis have shown that such behavior is enriched in a subpopulation of cells with stem cell-like features or tumor-initiating cells. The identification of drugs that t… Continue reading

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Lack of Survival Benefit following Liver Transplantation With MELD Exception Points for Hepatocellular Carcinoma: Beyond the Unblinding of Lady Justice

The ever-increasing success of liver transplantation as a life-saving procedure has led to the demand for donor organs far outstripping supply. Nearly 1 in 5 patients waiting for a liver transplant in the United States dies before an organ becomes avai… Continue reading

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