Monthly Archives: July 2015
Genetics and Genetic Testing in Hereditary Colorectal Cancer
Colorectal Cancer (CRC) remains the third most common cancer affecting men and women in the United States. Approximately one-third of CRCs are diagnosed in individuals who have family members also affected with the disease. While the vast majority of c… Continue reading
Genetics and Genetic Testing in Hereditary Colorectal Cancer
Colorectal Cancer (CRC) remains the third most common cancer affecting men and women in the United States. Approximately one-third of CRCs are diagnosed in individuals who have family members also affected with the disease. While the vast majority of c… Continue reading
Increasing the Impact of Randomized, Controlled Trials in Gastrointestinal Endoscopy
The randomized, controlled trial (RCT) is the cornerstone upon which clinical decision making and practice guidelines are based. RCTs are a crucial step in the scientific progression from bench to bedside, often representing the culmination of importan… Continue reading
Increasing the Impact of Randomized, Controlled Trials in Gastrointestinal Endoscopy
The randomized, controlled trial (RCT) is the cornerstone upon which clinical decision making and practice guidelines are based. RCTs are a crucial step in the scientific progression from bench to bedside, often representing the culmination of importan… Continue reading
Covering the Cover
In contrast with celiac disease, (CD) which is characterized by an immune-based reaction to gluten, primarily involving the small intestine, in genetically predisposed individuals, nonceliac gluten sensitivity or, more accurately, nonceliac wheat sensi… Continue reading
Digital Health: Hope, Hype, and Amara’s Law
We live in the digital age. Digital technology is changing all aspects of our lives, including how we work and spend our leisure time, how we relate to others, and even how we think. Although late compared with other industries, digital technologies ar… Continue reading
Digital Health: Hope, Hype, and Amara’s Law
We live in the digital age. Digital technology is changing all aspects of our lives, including how we work and spend our leisure time, how we relate to others, and even how we think. Although late compared with other industries, digital technologies ar… Continue reading
Next Generation Multigene Panel Testing: The Next step for identification of Hereditary Colorectal Cancer Syndromes?
This issue of Gastroenterology presents a manuscript by Yurgelun et al1 that addresses the question of whether multigene panel testing offers “meaningful advantages over targeted criteria-based genetic testing” in patients meeting criteria for the… Continue reading
Next Generation Multigene Panel Testing: The Next step for identification of Hereditary Colorectal Cancer Syndromes?
This issue of Gastroenterology presents a manuscript by Yurgelun et al1 that addresses the question of whether multigene panel testing offers “meaningful advantages over targeted criteria-based genetic testing” in patients meeting criteria for the… Continue reading
Trials and Tribulations: The Prevention of Variceal Rebleeding
The last 25 years of portal hypertension clinical research has directly resulted in a reduction in variceal bleeding mortality from 50% to 20%. This research has included introduction of new techniques, technological refinements, and application of old… Continue reading