Monthly Archives: July 2015
Trials and Tribulations: The Prevention of Variceal Rebleeding
The last 25 years of portal hypertension clinical research has directly resulted in a reduction in variceal bleeding mortality from 50% to 20%. This research has included introduction of new techniques, technological refinements, and application of old… Continue reading
c-Kit as a Novel Potential Therapeutic Target in Colorectal Cancer
Studies to identify the cells that fuel colorectal cancer (CRC) cell renewal and metastasis have shown that such behavior is enriched in a subpopulation of cells with stem cell-like features or tumor-initiating cells. The identification of drugs that t… Continue reading
c-Kit as a Novel Potential Therapeutic Target in Colorectal Cancer
Studies to identify the cells that fuel colorectal cancer (CRC) cell renewal and metastasis have shown that such behavior is enriched in a subpopulation of cells with stem cell-like features or tumor-initiating cells. The identification of drugs that t… Continue reading
Lack of Survival Benefit following Liver Transplantation With MELD Exception Points for Hepatocellular Carcinoma: Beyond the Unblinding of Lady Justice
The ever-increasing success of liver transplantation as a life-saving procedure has led to the demand for donor organs far outstripping supply. Nearly 1 in 5 patients waiting for a liver transplant in the United States dies before an organ becomes avai… Continue reading
Lack of Survival Benefit following Liver Transplantation With MELD Exception Points for Hepatocellular Carcinoma: Beyond the Unblinding of Lady Justice
The ever-increasing success of liver transplantation as a life-saving procedure has led to the demand for donor organs far outstripping supply. Nearly 1 in 5 patients waiting for a liver transplant in the United States dies before an organ becomes avai… Continue reading
The FXR-FGF19 Gut–Liver Axis as a Novel “Hepatostat”
The liver possesses an extraordinary regenerative capacity that is triggered upon death of parenchymal cells or after partial liver resection. This fundamental response likely evolved to protect the organ and the organism from endogenous and exogenous … Continue reading
The FXR-FGF19 Gut–Liver Axis as a Novel “Hepatostat”
The liver possesses an extraordinary regenerative capacity that is triggered upon death of parenchymal cells or after partial liver resection. This fundamental response likely evolved to protect the organ and the organism from endogenous and exogenous … Continue reading
Professor Claude C. Roy, October 21,1928–July 2, 2015
Claude Roy, the eminent Canadian physician and scientist, considered one of the founders of pediatric gastroenterology, died in Montreal on July 2, 2015 at the age of 86. He leaves behind a profound and lasting impression upon the spirit of those that … Continue reading
Professor Claude C. Roy, October 21,1928–July 2, 2015
Claude Roy, the eminent Canadian physician and scientist, considered one of the founders of pediatric gastroenterology, died in Montreal on July 2, 2015 at the age of 86. He leaves behind a profound and lasting impression upon the spirit of those that … Continue reading