Monthly Archives: July 2015
Epigenetic Alterations in Colorectal Cancer: Emerging Biomarkers
Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. One of the fundamental processes driving the initiation and progression of CRC is the accumulation of a variety of genetic and epigenetic changes in colon epithelial cells. Over the… Continue reading
Epigenetic Alterations in Colorectal Cancer: Emerging Biomarkers
Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. One of the fundamental processes driving the initiation and progression of CRC is the accumulation of a variety of genetic and epigenetic changes in colon epithelial cells. Over the… Continue reading
Serologic Assay for Diagnosis of Celiac Disease Based on a Patient-derived Monoclonal Anti-gliadin Antibody
Patients with celiac disease can be identified based on detection of serum antibodies to deamidated gliadin peptides (DGP). Recombinant human monoclonal antibodies (hmAb) against gliadin are produced by cloning antibody genes from single immunoglobulin… Continue reading
Serologic Assay for Diagnosis of Celiac Disease Based on a Patient-derived Monoclonal Anti-gliadin Antibody
Patients with celiac disease can be identified based on detection of serum antibodies to deamidated gliadin peptides (DGP). Recombinant human monoclonal antibodies (hmAb) against gliadin are produced by cloning antibody genes from single immunoglobulin… Continue reading
Statin Use Reduces Risk of Esophageal Adenocarcinoma in US Veterans With Barrett’s Esophagus: a Nested Case–Control Study
Statins have been reported to protect against esophageal adenocarcinoma (EAC) in patients with Barrett’s esophagus (BE). However, there are few data from adequately powered cohort studies of subjects with BE. Continue reading
Statin Use Reduces Risk of Esophageal Adenocarcinoma in US Veterans With Barrett’s Esophagus: a Nested Case–Control Study
Statins have been reported to protect against esophageal adenocarcinoma (EAC) in patients with Barrett’s esophagus (BE). However, there are few data from adequately powered cohort studies of subjects with BE. Continue reading
Genetic Insights in Barrett’s Esophagus and Esophageal Adenocarcinoma
Beginning in the 1980s, an alarming rise in the incidence of esophageal adenocarcinoma (EA) led to screening of patients with reflux to detect Barrett’s esophagus (BE) and surveillance of BE to detect early EA. This strategy, based on linear progress… Continue reading
Genetic Insights in Barrett’s Esophagus and Esophageal Adenocarcinoma
Beginning in the 1980s, an alarming rise in the incidence of esophageal adenocarcinoma (EA) led to screening of patients with reflux to detect Barrett’s esophagus (BE) and surveillance of BE to detect early EA. This strategy, based on linear progress… Continue reading