Daily Archives: August 6, 2015

STAT3 Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer

Posted on August 6, 2015 by Nagaraj S. Nagathihalli, Jason A. Castellanos, Chanjuan Shi, Yugandhar Beesetty, Michelle L. Reyzer, Richard Caprioli, Xi Chen, Alex J. Walsh, Melissa C. Skala, Harold L. Moses, Nipun B. Merchant

STAT3 inhibition combined with gemcitabine remodels the tumor stroma to enhance tumor drug delivery and improve survival in a genetic mouse model of pancreatic cancer. Continue reading →

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STAT3 Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer

Posted on August 6, 2015 by Nagaraj S. Nagathihalli, Jason A. Castellanos, Chanjuan Shi, Yugandhar Beesetty, Michelle L. Reyzer, Richard Caprioli, Xi Chen, Alex J. Walsh, Melissa C. Skala, Harold L. Moses, Nipun B. Merchant

STAT3 inhibition combined with gemcitabine remodels the tumor stroma to enhance tumor drug delivery and improve survival in a genetic mouse model of pancreatic cancer. Continue reading →

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Increased Risk of Functional Gastrointestinal Sequelae Following infection among Active Duty United States Military Personnel (1998-2010)

Posted on August 6, 2015 by Ramiro L. Gutiérrez, Mark S. Riddle, Chad K. Porter

Some acute enteric infections are associated with development of functional gastrointestinal disorders, most commonly irritable bowel syndrome, but also other functional and organic gastrointestinal sequelae. Clostridium difficile infection has increas… Continue reading →

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Increased Risk of Functional Gastrointestinal Sequelae Following infection among Active Duty United States Military Personnel (1998-2010)

Posted on August 6, 2015 by Ramiro L. Gutiérrez, Mark S. Riddle, Chad K. Porter

Some acute enteric infections are associated with development of functional gastrointestinal disorders, most commonly irritable bowel syndrome, but also other functional and organic gastrointestinal sequelae. Clostridium difficile infection has increas… Continue reading →

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Genetics of Inflammatory Bowel Diseases

Posted on August 6, 2015 by Dermot McGovern, Subra Kugathasan, Judy H. Cho

In this Review, we provide an update on genome-wide association studies (GWAS) in inflammatory bowel disease (IBD). In addition, we summarize progress in defining the functional consequences of associated alleles for coding and non-coding genetic varia… Continue reading →

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Genetics of Inflammatory Bowel Diseases

Posted on August 6, 2015 by Dermot McGovern, Subra Kugathasan, Judy H. Cho

In this Review, we provide an update on genome-wide association studies (GWAS) in inflammatory bowel disease (IBD). In addition, we summarize progress in defining the functional consequences of associated alleles for coding and non-coding genetic varia… Continue reading →

Posted in News | Comments Off on Genetics of Inflammatory Bowel Diseases