Daily Archives: September 12, 2015

Correlation Between Concentrations of Fecal Calprotectin and Outcomes of Patients With Ulcerative Colitis in a Phase 2 Trial

Posted on September 12, 2015 by William J. Sandborn, Julian Panés, Haiying Zhang, Dahong Yu, Wojciech Niezychowski, Chinyu Su

Accurate biomarkers of disease activity and therapeutic response can be valuable for clinical trials. We performed a post hoc analysis of data from a phase 2 trial to assess the relationship between the concentration of fecal calprotectin (FCP) and cl… Continue reading →

Posted in News | Comments Off on Correlation Between Concentrations of Fecal Calprotectin and Outcomes of Patients With Ulcerative Colitis in a Phase 2 Trial

Physiological Mechanisms of Weight Gain−Induced Steatosis in People With Obesity

Posted on September 12, 2015 by Elisa Fabbrini, Courtney Tiemann Luecking, Latisha Love-Gregory, Adewole L. Okunade, Mihoko Yoshino, Gemma Fraterrigo, Bruce W. Patterson, Samuel Klein

Weight gain is associated with an increase in intrahepatic triglycerides (IHTGs), and is the primary cause of nonalcoholic fatty liver disease in obese individuals. We combined imaging and stable isotope tracer techniques to evaluate the physiologic me… Continue reading →

Posted in News | Comments Off on Physiological Mechanisms of Weight Gain−Induced Steatosis in People With Obesity

Correlation Between Concentrations of Fecal Calprotectin and Outcomes of Patients With Ulcerative Colitis in a Phase 2 Trial

Posted on September 12, 2015 by William J. Sandborn, Julian Panés, Haiying Zhang, Dahong Yu, Wojciech Niezychowski, Chinyu Su

Accurate biomarkers of disease activity and therapeutic response can be valuable for clinical trials. We performed a post hoc analysis of data from a phase 2 trial to assess the relationship between the concentration of fecal calprotectin (FCP) and cl… Continue reading →

Posted in News | Comments Off on Correlation Between Concentrations of Fecal Calprotectin and Outcomes of Patients With Ulcerative Colitis in a Phase 2 Trial

Physiological Mechanisms of Weight Gain−Induced Steatosis in People With Obesity

Posted on September 12, 2015 by Elisa Fabbrini, Courtney Tiemann Luecking, Latisha Love-Gregory, Adewole L. Okunade, Mihoko Yoshino, Gemma Fraterrigo, Bruce W. Patterson, Samuel Klein

Weight gain is associated with an increase in intrahepatic triglycerides (IHTGs), and is the primary cause of nonalcoholic fatty liver disease in obese individuals. We combined imaging and stable isotope tracer techniques to evaluate the physiologic me… Continue reading →

Posted in News | Comments Off on Physiological Mechanisms of Weight Gain−Induced Steatosis in People With Obesity