Daily Archives: September 22, 2015

Sofosbuvir Inhibits Hepatitis E Virus Replication In Vitro and Results in an Additive Effect When Combined With Ribavirin

Posted on September 22, 2015 by Viet Loan Dao Thi, Yannick Debing, Xianfang Wu, Charles M. Rice, Johan Neyts, Darius Moradpour, Jérôme Gouttenoire

Infection with hepatitis E virus genotype 3 may result in chronic hepatitis in immunocompromised patients. Reduction of immunosuppression or treatment with ribavirin or pegylated interferon-α can result in viral clearance. However, safer and more effe… Continue reading →

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Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS

Posted on September 22, 2015 by Wanglong Qiu, Sophia M. Tang, Sohyae Lee, Andrew T. Turk, Anthony N. Sireci, Anne Qiu, Christian Rose, Chuangao Xie, Jan Kitajewski, Hui-Ju Wen, Howard C. Crawford, Peter A. Sims, Ralph H. Hruban, Helen E. Remotti, Gloria H. Su

Activin, a member of the transforming growth factor-β (TGFB) family, might be involved in pancreatic tumorigenesis, similar to other members of the TGFB family. Human pancreatic ductal adenocarcinomas contain somatic mutations in the activin A recep… Continue reading →

Posted in News | Comments Off on Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS

Sofosbuvir Inhibits Hepatitis E Virus Replication In Vitro and Results in an Additive Effect When Combined With Ribavirin

Posted on September 22, 2015 by Viet Loan Dao Thi, Yannick Debing, Xianfang Wu, Charles M. Rice, Johan Neyts, Darius Moradpour, Jérôme Gouttenoire

Infection with hepatitis E virus genotype 3 may result in chronic hepatitis in immunocompromised patients. Reduction of immunosuppression or treatment with ribavirin or pegylated interferon-α can result in viral clearance. However, safer and more effe… Continue reading →

Posted in News | Comments Off on Sofosbuvir Inhibits Hepatitis E Virus Replication In Vitro and Results in an Additive Effect When Combined With Ribavirin

Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS

Posted on September 22, 2015 by Wanglong Qiu, Sophia M. Tang, Sohyae Lee, Andrew T. Turk, Anthony N. Sireci, Anne Qiu, Christian Rose, Chuangao Xie, Jan Kitajewski, Hui-Ju Wen, Howard C. Crawford, Peter A. Sims, Ralph H. Hruban, Helen E. Remotti, Gloria H. Su

Activin, a member of the transforming growth factor-β (TGFB) family, might be involved in pancreatic tumorigenesis, similar to other members of the TGFB family. Human pancreatic ductal adenocarcinomas contain somatic mutations in the activin A recep… Continue reading →

Posted in News | Comments Off on Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS