Daily Archives: October 24, 2015

Inhibition of Tumor Growth and Metastasis in Pancreatic Cancer Models by Interference With CD44v6 Signaling

Posted on October 24, 2015 by Alexandra Matzke-Ogi, Katharina Jannasch, Marine Shatirishvili, Beatrix Fuchs, Sara Chiblak, Jennifer Morton, Bouchra Tawk, Thomas Lindner, Owen Sansom, Frauke Alves, Arne Warth, Christian Schwager, Walter Mier, Jörg Kleeff, Helmut Ponta, Amir Abdoll

Cancer cells with high metastatic potential and stem cell–like characteristics express the cell surface marker CD44. CD44 isoforms that include the v6 exon are co-receptors for the receptor tyrosine kinases MET and VEGFR-2. We studied CD44v6 signali… Continue reading →

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Inhibition of Tumor Growth and Metastasis in Pancreatic Cancer Models by Interference With CD44v6 Signaling

Posted on October 24, 2015 by Alexandra Matzke-Ogi, Katharina Jannasch, Marine Shatirishvili, Beatrix Fuchs, Sara Chiblak, Jennifer Morton, Bouchra Tawk, Thomas Lindner, Owen Sansom, Frauke Alves, Arne Warth, Christian Schwager, Walter Mier, Jörg Kleeff, Helmut Ponta, Amir Abdoll

Cancer cells with high metastatic potential and stem cell–like characteristics express the cell surface marker CD44. CD44 isoforms that include the v6 exon are co-receptors for the receptor tyrosine kinases MET and Vascular Endothelial Growth factor… Continue reading →

Posted in News | Comments Off on Inhibition of Tumor Growth and Metastasis in Pancreatic Cancer Models by Interference With CD44v6 Signaling