Monthly Archives: November 2015

It is not clear whether symptoms alone can be used to estimate the biologic activity of eosinophilic esophagitis (EoE). We aimed to evaluate whether symptoms can be used to identify patients with endoscopic and histologic features of remission. Continue reading →

Microscopic colitis (MC) is a cause of chronic diarrhea, and there are 2 subtypes: collagenous colitis (CC) and lymphocytic colitis (LC). The clinical features, symptoms, and responses to treatment are similar for both CC and LC. All meta-analyses cond… Continue reading →

Follicular T-helper (Tfh) cells contribute to pathogen-specific antibody responses by providing maturation signals to B cells. In mice with viral infections, virus-specific Tfh cells expand and are required to contain the infection. However, less is kn… Continue reading →

The risk of colorectal neoplasms among siblings of patients with advanced adenomas is not clear. We determined the prevalence of advanced adenomas in the siblings of patients with advanced adenomas and compared it with that of siblings of individuals w… Continue reading →

It is not clear whether symptoms alone can be used to estimate the biologic activity of eosinophilic esophagitis (EoE). We aimed to evaluate whether symptoms can be used to identify patients with endoscopic and histologic features of remission. Continue reading →

This document presents the official recommendations of the American Gastroenterological Association (AGA) Institute on the medical management of microscopic colitis. The guideline was developed by the AGA Clinical Guidelines Committee and approved by t… Continue reading →

Microscopic colitis (MC) is a cause of chronic diarrhea, and there are 2 subtypes: collagenous colitis (CC) and lymphocytic colitis (LC). The clinical features, symptoms, and responses to treatment are similar for both CC and LC. All meta-analyses cond… Continue reading →

Hereditary hemochromatosis is a heterogeneous group of genetic disorders characterized by parenchymal iron overload. It is caused by defective expression of liver hepcidin, the main regulator of iron homeostasis. Iron stimulates the gene encoding (HAMP… Continue reading →

Obesity and alcohol consumption contribute to steatohepatitis, which increases risk for hepatitis C virus (HCV)-associated hepatocellular carcinomas (HCCs). Mice Hepatocytes that express HCV-NS5A in liver upregulate expression of Toll-like receptor-4 (… Continue reading →

Hereditary hemochromatosis is a heterogeneous group of genetic disorders characterized by parenchymal iron overload. It is caused by defective expression of liver hepcidin, the main regulator of iron homeostasis. Iron stimulates the gene encoding hepci… Continue reading →