Monthly Archives: November 2015

Question: A 67-year-old woman, who is a hepatitis C virus carrier, suffered from early satiety, indigestion, and occasional abdominal fullness since 2013. Physical examination and laboratory tests were unremarkable. Esophagogastroduodenoscopy disclosed… Continue reading →

Question: A 48-year-old patient was referred for gastroscopy and colonoscopy because of anemia. Personal history was otherwise unremarkable except for Wolf-Parkinson-White syndrome. Gastroscopy showed a submucosal 2 × 4-cm tumor in the antrum with a … Continue reading →

Question: A 73-year-old male underwent screening colonoscopy. He has lived for a couple of years in Namibia on his farm and has gone several times on hunting safaris in other African countries. He was not aware of any serious diseases in the past excep… Continue reading →

Question: A 77-year-old man with ulcerative colitis was admitted to hospital with a 1-month history of recurrent fevers. He had a long-standing history of ulcerative pancolitis nonresponsive to mesalamine and azathioprine. After developing steroid dependence (minimal prednisone requirement 15 mg/d), he was started on infliximab approximately 4 months before admission, completing infliximab induction therapy (0, 2, and 6 weeks at 5 mg/kg) and receiving his first maintenance infusion (5 mg/kg). At presentation, the patient had multiple symptoms, including (1) recurrent daily fevers and chills, (2) severe bloody diarrhea (>15 bowel movements per day) with urge and tenesmus, and (3) subacute dyspnea and hypoxia requiring 4 L/min supplemental oxygen by nasal cannula. Continue reading →

A proportion of patients with Barrett’s esophagus (BE) are diagnosed with esophageal adenocarcinoma (EAC) within 1 year of an endoscopic examination that produced negative findings. These cases of missed cancers have not been well studied, despite cu… Continue reading →

Activation of WNT signaling promotes the invasive activities of several types of cancer cells, but little it is not clear if it regulates the same processes in colorectal cancer (CRC) cells, or what mechanisms are involved. We studied the expression an… Continue reading →

The text Endoscopy in Small Bowel Disorders, edited by Richard Kozarek and Jonathan A. Leighton and published by Springer in 2015, covers a range of small bowel imaging, common pathologic conditions of the small bowel, and management decisions and tech… Continue reading →

Pancreatic Cancer, Cystic Neoplasms, and Endocrine Tumors: Diagnosis and Management aims to present the most up-to-date information on surgical management of pancreatic tumors. Their intended audience is practicing surgeons and surgical trainees, altho… Continue reading →

A proportion of patients with Barrett’s esophagus (BE) are diagnosed with esophageal adenocarcinoma (EAC) within 1 year of an endoscopic examination that produced negative findings. These cases of missed cancers have not been well studied, despite cu… Continue reading →

Activation of WNT signaling promotes the invasive activities of several types of cancer cells, but it is not clear if it regulates the same processes in colorectal cancer (CRC) cells, or what mechanisms are involved. We studied the expression and funct… Continue reading →