Monthly Archives: November 2015

Question: A 9-month-old, previously healthy female infant presented with a 2-week history of watery diarrhea and tactile fevers. One day before admission, the mother noticed prolapsing rectal mucosa. The mother gave a history of amoxicillin treatment 2… Continue reading →

Question: A 57-year-old Japanese woman underwent esophagogastroduodenoscopy for further investigation of epigastric discomfort. The patient had been taking glucocorticoids for proteinuria owing to minimal change disease. She was also diagnosed with Sj Continue reading →

Question: A 33-year-old man presented with episodic melena for 3 months associated with worsening exertional dyspnea and lethargy for 2 weeks. Clinical examination revealed marked conjunctival pallor. No masses were felt on abdominal or rectal examinat… Continue reading →

Question: A 35-year-old woman presented with a 3-month history of postprandial abdominal discomfort and vomiting. The patient’s history included left jugular foramen schwannoma with involvement of the vagus and spinal accessory nerves (cranial nerves… Continue reading →

Nonalcoholic fatty liver disease (NAFLD) is the most common metabolic liver disease worldwide and the burden of NAFLD is likely to increase with the epidemic of obesity and type 2 diabetes. The term NAFLD embraces a spectrum of fat-related liver condit… Continue reading →

Nonalcoholic fatty liver disease (NAFLD) has emerged as a major cause of chronic liver disease in many parts of the world. It is associated with increased mortality owing to cardiovascular and liver disease and is also associated with an increased risk… Continue reading →

Reducing post-prandial triglyceridemia may be a promising strategy to lower risk of cardiovascular disorders associated with obesity and type 2 diabetes. In enterocytes, scavenger receptor class B, type 1 (SR-B1, encoded by SCARB1) mediates lipid-micel… Continue reading →

In 2007, the United States Preventive Services Task Force (USPSTF) recommended against the routine use of aspirin for the prevention of colorectal cancer (CRC). However, in September 2015, the USPSTF reversed this stand in its updated draft guidelines and provided low-dose aspirin (pragmatically, 81 mg/d in the United States) with a grade “B” recommendation for chronic disease prophylaxis, including CRC prevention, among US adults between ages 50 and 59 with a >10% 10-year risk of cardiovascular (CVD) events. Continue reading →

Patients with irritable bowel syndrome (IBS) have increased postprandial symptom responses and more psychosocial morbidities than healthy individuals. However, the relationship between psychosocial status and postprandial symptom responses has not been… Continue reading →

Reducing postprandial triglyceridemia may be a promising strategy to lower the risk of cardiovascular disorders associated with obesity and type 2 diabetes. In enterocytes, scavenger receptor class B, type 1 (SR-B1, encoded by SCARB1) mediates lipid-mi… Continue reading →