Monthly Archives: December 2015

Expression of Activated Ras in Gastric Chief Cells of Mice Leads to the Full Spectrum of Metaplastic Lineage Transitions

Gastric cancer develops in the context of parietal cell loss, spasmolytic polypeptide-expressing metaplasia (SPEM), and intestinal metaplasia (IM). We investigated whether expression of the activated form of Ras in gastric chief cells of mice leads to … Continue reading

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Magnetic Resonance Imaging More Accurately Classifies Steatosis and Fibrosis in Patients with Nonalcoholic Fatty Liver Disease Than Transient Elastography

Noninvasive methods have been evaluated for the assessment of liver fibrosis and steatosis in patients with nonalcoholic fatty liver disease (NAFLD). We compared the ability of clinical scoring systems, transient elastography (TE) with the M probe, and… Continue reading

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Correction

Neto R, Ferdinande L, Hindryckx P. Not a usual flare up of ulcerative colitis. Gastroenterology 2015;148:1284–1287. Continue reading

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Human Enteroids as a Model of Upper Small Intestinal Ion Transport Physiology and Pathophysiology

Human intestinal crypt-derived enteroids are a model of intestinal ion transport that require validation by comparison with cell culture and animal models. We used human small intestinal enteroids to study neutral Na+ absorption and stimulated fluid an… Continue reading

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Increased Risk of Colorectal Cancer Development Among Patients With Serrated Polyps

Sessile serrated adenomas/polyps (SSA/Ps) and traditional serrated adenomas (TSAs) are now distinguished from hyperplastic polyps and recognized as precursors to colorectal cancer (CRC). We studied CRC risks associated with serrated polyps. Continue reading

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Expression of Activated Ras in Gastric Chief Cells of Mice Leads to the Full Spectrum of Metaplastic Lineage Transitions

Gastric cancer develops in the context of parietal cell loss, spasmolytic polypeptide-expressing metaplasia (SPEM), and intestinal metaplasia (IM). We investigated whether expression of the activated form of Ras in gastric chief cells of mice leads to… Continue reading

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Magnetic Resonance Imaging More Accurately Classifies Steatosis and Fibrosis in Patients With Nonalcoholic Fatty Liver Disease Than Transient Elastography

Noninvasive methods have been evaluated for the assessment of liver fibrosis and steatosis in patients with nonalcoholic fatty liver disease (NAFLD). We compared the ability of clinical scoring systems, transient elastography (TE) with the M-probe, and… Continue reading

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Circadian Clock Control of Liver Metabolic Functions

The circadian clock is an endogenous biological timekeeping system that synchronizes physiology and behavior to day-night cycles. A wide variety of processes throughout the entire gastrointestinal tract and notably the liver appear to be under circadia… Continue reading

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Intracavitary Contrast-enhanced Ultrasonography to Detect Enterovesical Fistula in Crohn’s Disease

Enterovesical fistula is a relatively rare condition complicating Crohn’s disease (CD) that often requires surgical treatment.1 Ascertaining the presence of fistula and visualization of its anatomy are important for undertaking a decision for surgery… Continue reading

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Circadian Clock Control of Liver Metabolic Functions

The circadian clock is an endogenous biological timekeeping system that synchronizes physiology and behavior to day/night cycles. A wide variety of processes throughout the entire gastrointestinal tract and notably the liver appear to be under circadia… Continue reading

Posted in News | Comments Off on Circadian Clock Control of Liver Metabolic Functions