Monthly Archives: January 2016

A Challenging Case of Splenomegaly and Refractory Thrombocytopenia

Posted on January 28, 2016 by

Question: A 59-year-old man presented with a 2-week history of left-sided dull abdominal pain. He denied having diarrhea, fever, or weight loss. Physical examination revealed an enlarged spleen 3 cm below the costal margin. Complete blood count reveale… Continue reading →

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A Challenging Case of Splenomegaly and Refractory Thrombocytopenia

Posted on January 28, 2016 by

Question: A 59-year-old man presented with a 2-week history of left-sided dull abdominal pain. He denied having diarrhea, fever, or weight loss. Physical examination revealed an enlarged spleen 3 cm below the costal margin. Complete blood count reveale… Continue reading →

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Important Study Adds to Understanding of the Pathophysiology of Visceral Hypersensitivity but Raises More Questions Than it Answers

Posted on January 28, 2016 by Gintautas Grabauskas

I read with great interest the article by Cenac et al1 exploring the hypothesis that an increased level of 5(6)-epoxy-8Z,11Z,14Z-eicosatrienoic acid (5,6-EET) that stimulates transient receptor potential channel 4 (TRPV4) receptors cause hyperexcitabi… Continue reading →

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Important Study Adds to Understanding of the Pathophysiology of Visceral Hypersensitivity but Raises More Questions Than it Answers

Posted on January 28, 2016 by Gintautas Grabauskas

I read with great interest the article by Cenac et al1 exploring the hypothesis that an increased level of 5(6)-epoxy-8Z,11Z,14Z-eicosatrienoic acid (5,6-EET) that stimulates transient receptor potential channel 4 (TRPV4) receptors cause hyperexcitabi… Continue reading →

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An Unusual Cause of Severe Chest Pain

Posted on January 28, 2016 by

Question: A 74-year-old woman with a history of hypertension presented with a sudden onset of severe pain in the chest, progressive dysphagia, and vomiting. She had no previous history of symptoms related to her upper gastrointestinal tract. Physical e… Continue reading →

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An Unusual Cause of Severe Chest Pain

Posted on January 28, 2016 by

Question: A 74-year-old woman with a history of hypertension presented with a sudden onset of severe pain in the chest, progressive dysphagia, and vomiting. She had no previous history of symptoms related to her upper gastrointestinal tract. Physical e… Continue reading →

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An Unusual Cause of Right Upper Quadrant Pain in a Patient With Prior Liver Transplantation for Primary Sclerosing Cholangitis

Posted on January 28, 2016 by

Question: A 63-year-old man was referred for outpatient endoscopic ultrasound examination (EUS) to evaluate a pancreatic cyst. His past medical history was notable for ulcerative colitis requiring colectomy and primary sclerosing cholangitis (PSC) cirr… Continue reading →

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An Unusual Cause of Right Upper Quadrant Pain in a Patient With Prior Liver Transplantation for Primary Sclerosing Cholangitis

Posted on January 28, 2016 by

Question: A 63-year-old man was referred for outpatient endoscopic ultrasound examination (EUS) to evaluate a pancreatic cyst. His past medical history was notable for ulcerative colitis requiring colectomy and primary sclerosing cholangitis (PSC) cirr… Continue reading →

Posted in News | Comments Off on An Unusual Cause of Right Upper Quadrant Pain in a Patient With Prior Liver Transplantation for Primary Sclerosing Cholangitis

Unexpected Connection With a Diverticular Abscess

Posted on January 28, 2016 by

Question: A 55-year-old man, who had no previous abdominal surgery or known gallstones, was admitted to the hospital for epigastric pain, jaundice, and intermittent fevers for a week. Physical examination of an afebrile, jaundiced patient revealed a te… Continue reading →

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Unexpected Connection With a Diverticular Abscess

Posted on January 28, 2016 by

Question: A 55-year-old man, who had no previous abdominal surgery or known gallstones, was admitted to the hospital for epigastric pain, jaundice, and intermittent fevers for a week. Physical examination of an afebrile, jaundiced patient revealed a te… Continue reading →

Posted in News | Comments Off on Unexpected Connection With a Diverticular Abscess