Daily Archives: February 16, 2016
Terlipressin plus albumin is more effective than albumin alone in improving renal function in patients with cirrhosis and hepatorenal syndrome type 1
Hepatorenal syndrome type 1 (HRS-1) in patients with cirrhosis and ascites is a functional, potentially reversible form of acute kidney injury characterized by rapid (<2 weeks) and progressive deterioration of renal function. Terlipressin is a synthetic vasopressin analogue that acts, via vascular vasopressin V1 receptors, as a systemic vasoconstrictor. We performed a phase 3 study to evaluate the efficacy and safety of intravenous terlipressin plus albumin vs placebo plus albumin in patients with HRS-1. Continue reading
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Terlipressin plus albumin is more effective than albumin alone in improving renal function in patients with cirrhosis and hepatorenal syndrome type 1
Hepatorenal syndrome type 1 (HRS-1) in patients with cirrhosis and ascites is a functional, potentially reversible form of acute kidney injury characterized by rapid (<2 weeks) and progressive deterioration of renal function. Terlipressin is a synthetic vasopressin analogue that acts, via vascular vasopressin V1 receptors, as a systemic vasoconstrictor. We performed a phase 3 study to evaluate the efficacy and safety of intravenous terlipressin plus albumin vs placebo plus albumin in patients with HRS-1. Continue reading
Posted in News
Comments Off on Terlipressin plus albumin is more effective than albumin alone in improving renal function in patients with cirrhosis and hepatorenal syndrome type 1
Esophageal Expression of Active IκB kinase-β in Mice Upregulates Tumor Necrosis Factor and Granulocyte Macrophage Colony-stimulating Factor, Promoting Inflammation and Angiogenesis
IκB kinase-β (IKKβ) mediates activation of the nuclear factor-κB (NFκB), which regulates immune and inflammatory responses. Although NFκB is activated in cells from patients with inflammatory diseases or cancer, little is known about its roles in… Continue reading
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Esophageal Expression of Active IκB kinase-β in Mice Upregulates Tumor Necrosis Factor and Granulocyte Macrophage Colony-stimulating Factor, Promoting Inflammation and Angiogenesis
IκB kinase-β (IKKβ) mediates activation of the nuclear factor-κB (NFκB), which regulates immune and inflammatory responses. Although NFκB is activated in cells from patients with inflammatory diseases or cancer, little is known about its roles in… Continue reading
Posted in News
Comments Off on Esophageal Expression of Active IκB kinase-β in Mice Upregulates Tumor Necrosis Factor and Granulocyte Macrophage Colony-stimulating Factor, Promoting Inflammation and Angiogenesis