Daily Archives: April 5, 2016

Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice

Posted on April 5, 2016 by Kirk Bergstrom, Xiaowei Liu, Yiming Zhao, Nan Gao, Qian Wu, Kai Song, Yi Cui, Yun Li, J. Michael McDaniel, Samuel McGee, Weichang Chen, Mark M. Huycke, Courtney W. Houchen, Lauren A. Zenewicz, Christopher M. West, Hong Chen, Jonathan Braun, Jianxin F

Core 1– and core 3–derived mucin-type O-linked oligosaccharides (O-glycans) are major components of the colonic mucus layer. Defective forms of colonic O-glycans, such as the Thomsen-nouveau (Tn) antigen, frequently are observed in patients with ul… Continue reading →

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Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice

Posted on April 5, 2016 by Kirk Bergstrom, Xiaowei Liu, Yiming Zhao, Nan Gao, Qian Wu, Kai Song, Yi Cui, Yun Li, J. Michael McDaniel, Samuel McGee, Weichang Chen, Mark M. Huycke, Courtney W. Houchen, Lauren A. Zenewicz, Christopher M. West, Hong Chen, Jonathan Braun, Jianxin F

Core 1– and core 3–derived mucin-type O-linked oligosaccharides (O-glycans) are major components of the colonic mucus layer. Defective forms of colonic O-glycans, such as the Thomsen-nouveau (Tn) antigen, frequently are observed in patients with ul… Continue reading →

Posted in News | Comments Off on Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice