Monthly Archives: May 2016

The METEOR Trial: The Burial of Methotrexate in Ulcerative Colitis?

We read with interest the recent work by Carbonnel et al1 reporting the results from the METEOR (Controlled, Randomized, Double-Blind, Multicentre Study Comparing Methotrexate vs Placebo in Steroid Dependant Ulcerative Colitis) trial. We agree with th… Continue reading

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The METEOR Trial: The Burial of Methotrexate in Ulcerative Colitis?

We read with interest the recent work by Carbonnel et al1 reporting the results from the METEOR (Controlled, Randomized, Double-Blind, Multicentre Study Comparing Methotrexate vs Placebo in Steroid Dependant Ulcerative Colitis) trial. We agree with th… Continue reading

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We thank Pattou, Daoudi, and Baud for their interest in our work,1 as well as for their complementary work,2 on intestinal absorption of ingested glucose after Roux-en-Y gastric bypass (RYGB). Based on their recent data obtained with a minipig model of… Continue reading

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We thank Pattou, Daoudi, and Baud for their interest in our work,1 as well as for their complementary work,2 on intestinal absorption of ingested glucose after Roux-en-Y gastric bypass (RYGB). Based on their recent data obtained with a minipig model of… Continue reading

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A Hazard of Outdoor Grilling

Question: A 63-year-old woman with a 6-year history of fibrostenotic ileocolonic Crohn’s disease (CD) presented for evaluation after multiple hospitalizations for recurrent small bowel obstruction (SBO). Treatment for CD included adalimumab and azath… Continue reading

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A Hazard of Outdoor Grilling

Question: A 63-year-old woman with a 6-year history of fibrostenotic ileocolonic Crohn’s disease (CD) presented for evaluation after multiple hospitalizations for recurrent small bowel obstruction (SBO). Treatment for CD included adalimumab and azath… Continue reading

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We thank Macaluso et al for their comments about our study on methotrexate in steroid-dependent ulcerative colitis (UC).1 In this trial, parenteral methotrexate was not superior to placebo, using a composite primary endpoint consisting of clinical and… Continue reading

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We thank Macaluso et al for their comments about our study on methotrexate in steroid-dependent ulcerative colitis (UC).1 In this trial, parenteral methotrexate was not superior to placebo, using a composite primary endpoint consisting of clinical and… Continue reading

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Integrin αEβ7 in Inflammatory Bowel Disease: Friend or Foe?

We read with great interest the article by Tew et al1 on the association between increased gene expression of integrin αE and granzyme A (GZMA) and clinical remission to etrolizumab treatment in patients with ulcerative colitis (UC). This report foll… Continue reading

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Integrin αEβ7 in Inflammatory Bowel Disease: Friend or Foe?

We read with great interest the article by Tew et al1 on the association between increased gene expression of integrin αE and granzyme A (GZMA) and clinical remission to etrolizumab treatment in patients with ulcerative colitis (UC). This report foll… Continue reading

Posted in News | Comments Off on Integrin αEβ7 in Inflammatory Bowel Disease: Friend or Foe?