Monthly Archives: May 2016
How to Select a Mentor as a Trainee and Junior Faculty
The delicate balance of mentoring someone is not creating them in your own image, but giving them the opportunity to create themselves.Steven Spielberg Continue reading
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How to Select a Mentor as a Trainee and Junior Faculty
The delicate balance of mentoring someone is not creating them in your own image, but giving them the opportunity to create themselves.Steven Spielberg Continue reading
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The Dawning of a New Editorial Board for Gastroenterology
Change. An old adage stipulates it is the one true constant in life, or, stated another way, “Change is inevitable-except from a vending machine” (Robert Gallagher). On behalf of our new Board of Editors, we are honored, humbled, and excited to ove… Continue reading
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The Dawning of a New Editorial Board for Gastroenterology
Change. An old adage stipulates it is the one true constant in life, or, stated another way, “Change is inevitable-except from a vending machine” (Robert Gallagher). On behalf of our new Board of Editors, we are honored, humbled, and excited to ove… Continue reading
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YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK–STAT3 Signaling
Pancreatitis is the most important risk factor for pancreatic ductal adenocarcinoma (PDAC). Pancreatitis predisposes to PDAC because it induces a process of acinar cell reprogramming known as acinar-to-ductal metaplasia (ADM)—a precursor of pancreati… Continue reading
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YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Upregulation of JAK–STAT3 Signaling
Pancreatitis is the most important risk factor for pancreatic ductal adenocarcinoma (PDAC). Pancreatitis predisposes to PDAC because it induces a process of acinar cell reprogramming known as acinar-to-duct metaplasia (ADM)—a precursor of pancreatic … Continue reading
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Administration of Gemcitabine After Pancreatic Tumor Resection in Mice Induces an Antitumor Immune Response Mediated by Natural Killer Cells
Even after potentially curative R0 resection, patients with pancreatic ductal adenocarcinoma (PDAC) have a poor prognosis owing to high rates of local recurrence and metastasis to distant organs. However, we have no suitable transgenic animal models fo… Continue reading
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Administration of Gemcitabine After Pancreatic Tumor Resection in Mice Induces an Antitumor Immune Response Mediated by Natural Killer Cells
Even after potentially curative R0 resection, patients with pancreatic ductal adenocarcinoma (PDAC) have a poor prognosis owing to high rates of local recurrence and metastasis to distant organs. However, we have no suitable transgenic animal models fo… Continue reading
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Two-Step Forward Genetic Screen in Mice Identifies Ral GTPase-Activating Proteins as Suppressors of Hepatocellular Carcinoma
High-throughput sequencing technologies have identified thousands of infrequently mutated genes in hepatocellular carcinomas (HCCs). However, high intratumor and intertumor heterogeneity, combined with large numbers of passenger mutations, have made it… Continue reading
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Two-Step Forward Genetic Screen in Mice Identifies Ral GTPase-Activating Proteins as Suppressors of Hepatocellular Carcinoma
High-throughput sequencing technologies have identified thousands of infrequently mutated genes in hepatocellular carcinomas (HCCs). However, high intratumor and intertumor heterogeneity, combined with large numbers of passenger mutations, have made it… Continue reading
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Comments Off on Two-Step Forward Genetic Screen in Mice Identifies Ral GTPase-Activating Proteins as Suppressors of Hepatocellular Carcinoma