Monthly Archives: June 2016
ADAR-Mediated RNA Editing Predicts Progression and Prognosis of Gastric Cancer
Gastric cancer (GC) is the third leading cause of global cancer mortality. Adenosine-to-inosine RNA editing is a recently described novel epigenetic mechanism involving sequence alterations at the RNA but not DNA level, primarily mediated by ADAR (aden… Continue reading
ADAR-mediated RNA editing predicts progression and prognosis of Gastric Cancer
Gastric cancer (GC) is the third leading cause of global cancer mortality. Adenosine-to-Inosine (A-to-I) RNA editing is a recently-described novel epigenetic mechanism involving sequence alterations at the RNA but not DNA level, primarily mediated by A… Continue reading
Four Approaches to Reinvigorate Learning for the 21st Century Gastroenterologist
Medical education has traditionally been delivered in fixed blocks of time during one’s professional career, often in static, live, learning venues. This scenario is quickly changing owing to the increased use of technology in medical education, a gr… Continue reading
Four Approaches to Reinvigorate Learning for the 21st Century Gastroenterologist
Medical education has traditionally been delivered in fixed blocks of time during one’s professional career, often in static, live, learning venues. This scenario is quickly changing owing to the increased use of technology in medical education, a gr… Continue reading
Duodenal Bacteria From Patients With Celiac Disease and Healthy Subjects Distinctly Affect Gluten Breakdown and Immunogenicity
Partially degraded gluten peptides from cereals trigger celiac disease (CD), an autoimmune enteropathy occurring in genetically susceptible persons. Susceptibility genes are necessary but not sufficient to induce CD, and additional environmental factor… Continue reading
Duodenal bacteria from patients with celiac disease and healthy subjects distinctly affect gluten breakdown and immunogenicity
Partially-degraded gluten peptides from cereals trigger celiac disease (CeD), an autoimmune enteropathy occuring in genetically susceptible persons. Susceptibility genes are necessary but not sufficient to induce CeD and additional environmental factor… Continue reading
Genetic Complexity of Crohn’s Disease in Two Large Ashkenazi Jewish Families
Crohn’s disease (CD) is a highly heritable disease that is particularly common in the Ashkenazi Jewish population. We studied 2 large Ashkenazi Jewish families with a high prevalence of CD in an attempt to identify novel genetic risk variants. Continue reading
Genetic Complexity of Crohn’s Disease in 2 Large Ashkenazi Jewish Families
Crohn’s disease (CD) is a highly heritable disease that is particularly common in the Ashkenazi Jewish population. We studied 2 large Ashkenazi Jewish families with a high prevalence of CD in an attempt to identify novel genetic risk variants. Continue reading
Pneumococcal Disease in Inflammatory Bowel Disease: Justification to Vaccinate at Diagnosis
Kantsø B, Simonsen J, Hoffmann S, et al. Inflammatory bowel disease patients are at increased risk of invasive pneumococcal disease: a nationwide Danish cohort study 1977-2013. Am J Gastroenterol 2015;110:1582–1587. Continue reading
Pneumococcal Disease in Inflammatory Bowel Disease: Justification to Vaccinate at Diagnosis
Kantsø B, Simonsen J, Hoffmann S, et al. Inflammatory bowel disease patients are at increased risk of invasive pneumococcal disease: a nationwide Danish cohort study 1977-2013. Am J Gastroenterol 2015;110:1582–1587. Continue reading