Daily Archives: June 21, 2016

Prevalence of Sclerosing Cholangitis Detected by Magnetic Resonance Cholangiography in Patients With Long-term Inflammatory Bowel Disease

Posted on June 21, 2016 by

The prevalence of primary sclerosing cholangitis (PSC) among patients with inflammatory bowel disease (IBD) is unclear. Patients with IBD might be screened for PSC using magnetic resonance cholangiography (MRC). We aimed to estimate the frequency and d… Continue reading →

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Prevalence of Sclerosing Cholangitis, Detected by Magnetic Resonance Cholangiography, in Patients with Long-term Inflammatory Bowel Disease

Posted on June 21, 2016 by

The prevalence of primary sclerosing cholangitis (PSC) among patients with inflammatory bowel disease (IBD) is unclear. Patients with IBD might be screened for PSC using magnetic resonance cholangiography (MRC). We aimed to estimate the frequency and d… Continue reading →

Posted in News | Comments Off on Prevalence of Sclerosing Cholangitis, Detected by Magnetic Resonance Cholangiography, in Patients with Long-term Inflammatory Bowel Disease

Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol

Posted on June 21, 2016 by Khalidur Rahman, Chirayu Desai, Smita S. Iyer, Natalie E. Thorn, Pradeep Kumar, Yunshan Liu, Tekla Smith, Andrew S. Neish, Hongliang Li, Shiyun Tan, Pengbo Wu, Xiaoxiong Liu, Yuanjie Yu, Alton B. Farris, Asma Nusrat, Charles A. Parkos, Frank A. Anani

There is evidence from clinical studies that compromised intestinal epithelial permeability contributes to the development of nonalcoholic steatohepatitis (NASH), but the exact mechanisms are not clear. Mice with disruption of the gene (F11r) encoding … Continue reading →

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Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol

Posted on June 21, 2016 by Khalidur Rahman, Chirayu Desai, Smita S. Iyer, Natalie E. Thorn, Pradeep Kumar, Yunshan Liu, Tekla Smith, Andrew S. Neish, Hongliang Li, Shiyun Tan, Pengbo Wu, Xiaoxiong Liu, Yuanjie Yu, Alton B. Farris, Asma Nusrat, Charles A. Parkos, Frank A. Anani

There is evidence from clinical studies that compromised intestinal epithelial permeability contributes to the development of non-alcoholic steatohepatitis (NASH), but the exact mechanisms are not clear. Mice with disruption of the gene (F11r) encoding… Continue reading →

Posted in News | Comments Off on Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol

Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Causes Loss of Stem Cells

Posted on June 21, 2016 by Martijn AJ. Koppens, Gergana Bounova, Gaetano Gargiulo, Ellen Tanger, Hans Janssen, Paulien Cornelissen-Steijger, Marleen Blom, Ji-Ying Song, Lodewyk F. Wessels, Maarten van Lohuizen

The polycomb repressive complex 2 (PRC2) regulates differentiation by contributing to repression of gene expression and thereby stabilizing the fate of stem cells and their progeny. PRC2 helps to maintain adult stem cell populations, but little is know… Continue reading →

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Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Causes Loss of Stem Cells

Posted on June 21, 2016 by Martijn AJ. Koppens, Gergana Bounova, Gaetano Gargiulo, Ellen Tanger, Hans Janssen, Paulien Cornelissen-Steijger, Marleen Blom, Ji-Ying Song, Lodewyk F. Wessels, Maarten van Lohuizen

The polycomb repressive complex 2 (PRC2) regulates differentiation by contributing to repression of gene expression and thereby stabilizing the fate of stem cells and their progeny. PRC2 helps to maintain adult stem cell populations, but little is know… Continue reading →

Posted in News | Comments Off on Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Causes Loss of Stem Cells