Daily Archives: June 22, 2016

Detection of Hot-Spot Mutations in Circulating Cell-Free DNA From Patients With Intraductal Papillary Mucinous Neoplasms of the Pancreas

Posted on June 22, 2016 by Andreas W. Berger, Daniel Schwerdel, Ivan G. Costa, Thilo Hackert, Oliver Strobel, Sandra Lam, Thomas F. Barth, Bernd Schröppel, Alexander Meining, Markus W. Büchler, Martin Zenke, Patrick C. Hermann, Thomas Seufferlein, Alexander Kleger

Intraductal papillary mucinous neoplasms (IPMNs) are the most frequent cystic pancreatic tumors. Little is known about their molecular alterations, but mutations in GNAS have been reported to promote IPMN formation. A tumor-derived fraction of circulat… Continue reading →

Posted in News | Comments Off on Detection of Hot-Spot Mutations in Circulating Cell-Free DNA From Patients With Intraductal Papillary Mucinous Neoplasms of the Pancreas

Detection of Hot-Spot Mutations in Circulating Cell-Free DNA From Patients With Intraductal Papillary Mucinous Neoplasms of the Pancreas

Posted on June 22, 2016 by Andreas W. Berger, Daniel Schwerdel, Ivan G. Costa, Thilo Hackert, Oliver Strobel, Sandra Lam, Thomas F. Barth, Bernd Schröppel, Alexander Meining, Markus W. Büchler, Martin Zenke, Patrick C. Hermann, Thomas Seufferlein, Alexander Kleger

Intraductal papillary mucinous neoplasms (IPMNs) are the most frequent cystic pancreatic tumors. Little is known about their molecular alterations, but mutations in GNAS have been reported to promote IPMN formation. A tumor-derived fraction of circulat… Continue reading →

Posted in News | Comments Off on Detection of Hot-Spot Mutations in Circulating Cell-Free DNA From Patients With Intraductal Papillary Mucinous Neoplasms of the Pancreas

Opportunities and Challenges for Pancreatic Circulating Tumor Cells

Posted on June 22, 2016 by Sunitha Nagrath, Rhonda M. Jack, Vaibhav Sahai, Diane M. Simeone

Sensitive and reproducible platforms have been developed for detection, isolation, and enrichment of circulating tumor cells (CTCs)—rare cells that enter the blood from solid tumors, including those of the breast, prostate gland, lung, pancreas, and … Continue reading →

Posted in News | Comments Off on Opportunities and Challenges for Pancreatic Circulating Tumor Cells

Opportunities and Challenges for Circulating Pancreatic Tumor Cells

Posted on June 22, 2016 by Sunitha Nagrath, Rhonda M. Jack, Vaibhav Sahai, Diane M. Simeone

Sensitive and reproducible platforms have been developed for detection, isolation, and enrichment of circulating tumor cells (CTCs)—rare cells that enter the blood from solid tumors, including those of the breast, prostate, lung, pancreas, and colon…. Continue reading →

Posted in News | Comments Off on Opportunities and Challenges for Circulating Pancreatic Tumor Cells