Daily Archives: June 29, 2016

Gemcitabine Activates Natural Killer Cells to Attenuate Pancreatic Cancer Recurrence

With an overall 5-year survival rate of only 7%, pancreatic ductal adenocarcinoma (PDA) has now eclipsed breast cancer as the third leading cause of cancer death in the United States1 and it is predicted to be second by 2030.2 Despite improvements in s… Continue reading

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Gemcitabine Activates Natural Killer Cells to Attenuate Pancreatic Cancer Recurrence

With an overall 5-year survival rate of only 7%, pancreatic ductal adenocarcinoma (PDA) has now eclipsed breast cancer as the third leading cause of cancer death in the United States1 and it is predicted to be second by 2030.2 Despite improvements in s… Continue reading

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Exam 3: Genomic Alterations Observed in Colitis-Associated Cancers Are Distinct From Those Found in Sporadic Colorectal Cancers and Vary by Type of Inflammatory Bowel Disease

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Exam 3: Genomic Alterations Observed in Colitis-Associated Cancers Are Distinct From Those Found in Sporadic Colorectal Cancers and Vary by Type of Inflammatory Bowel Disease

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PPIs and Chronic Kidney Disease: Another Association to Worry About?

Lazarus B, Chen Y, Wilson FP, et al. Proton pump inhibitor use and the risk of chronic kidney disease. JAMA Intern Med 2016;176:238–246. Continue reading

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PPIs and Chronic Kidney Disease: Another Association to Worry About?

Lazarus B, Chen Y, Wilson FP, et al. Proton pump inhibitor use and the risk of chronic kidney disease. JAMA Intern Med 2016;176:238–246. Continue reading

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Exam 2: Unraveling a Patient’s Postoperative Symptoms

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Concurrent Lower Gastrointestinal Bleeding Risk and Myocardial Ischemic Risk: Resume Aspirin or Not?

Teleologically, when there is bleeding, the natural response of the body is to promote clotting. This makes perfect sense if there is external injury that leads to bleeding and the response is also useful for some forms of internal “injury,” such a… Continue reading

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Concurrent Lower Gastrointestinal Bleeding Risk and Myocardial Ischemic Risk: Resume Aspirin or Not?

Teleologically, when there is bleeding, the natural response of the body is to promote clotting. This makes perfect sense if there is external injury that leads to bleeding and the response is also useful for some forms of internal “injury,” such a… Continue reading

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Two-Step Forward Genetic Screen in Mice Identifies the Ral Pathway as a Central Drug Target in Hepatocellular Carcinoma

A detailed understanding of the genetic background of hepatocellular carcinoma (HCC) will be crucial to developing new therapies aimed at selected targets.1 Given the sparse treatment options of advanced HCC, such progress is needed urgently for this h… Continue reading

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