Daily Archives: June 30, 2016

ADAR-Mediated RNA Editing Predicts Progression and Prognosis of Gastric Cancer

Gastric cancer (GC) is the third leading cause of global cancer mortality. Adenosine-to-inosine RNA editing is a recently described novel epigenetic mechanism involving sequence alterations at the RNA but not DNA level, primarily mediated by ADAR (aden… Continue reading

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ADAR-mediated RNA editing predicts progression and prognosis of Gastric Cancer

Gastric cancer (GC) is the third leading cause of global cancer mortality. Adenosine-to-Inosine (A-to-I) RNA editing is a recently-described novel epigenetic mechanism involving sequence alterations at the RNA but not DNA level, primarily mediated by A… Continue reading

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Four Approaches to Reinvigorate Learning for the 21st Century Gastroenterologist

Medical education has traditionally been delivered in fixed blocks of time during one’s professional career, often in static, live, learning venues. This scenario is quickly changing owing to the increased use of technology in medical education, a gr… Continue reading

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Four Approaches to Reinvigorate Learning for the 21st Century Gastroenterologist

Medical education has traditionally been delivered in fixed blocks of time during one’s professional career, often in static, live, learning venues. This scenario is quickly changing owing to the increased use of technology in medical education, a gr… Continue reading

Posted in News | Comments Off on Four Approaches to Reinvigorate Learning for the 21st Century Gastroenterologist

Duodenal Bacteria From Patients With Celiac Disease and Healthy Subjects Distinctly Affect Gluten Breakdown and Immunogenicity

Partially degraded gluten peptides from cereals trigger celiac disease (CD), an autoimmune enteropathy occurring in genetically susceptible persons. Susceptibility genes are necessary but not sufficient to induce CD, and additional environmental factor… Continue reading

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Duodenal bacteria from patients with celiac disease and healthy subjects distinctly affect gluten breakdown and immunogenicity

Partially-degraded gluten peptides from cereals trigger celiac disease (CeD), an autoimmune enteropathy occuring in genetically susceptible persons. Susceptibility genes are necessary but not sufficient to induce CeD and additional environmental factor… Continue reading

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Genetic Complexity of Crohn’s Disease in Two Large Ashkenazi Jewish Families

Crohn’s disease (CD) is a highly heritable disease that is particularly common in the Ashkenazi Jewish population. We studied 2 large Ashkenazi Jewish families with a high prevalence of CD in an attempt to identify novel genetic risk variants. Continue reading

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Genetic Complexity of Crohn’s Disease in 2 Large Ashkenazi Jewish Families

Crohn’s disease (CD) is a highly heritable disease that is particularly common in the Ashkenazi Jewish population. We studied 2 large Ashkenazi Jewish families with a high prevalence of CD in an attempt to identify novel genetic risk variants. Continue reading

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Pneumococcal Disease in Inflammatory Bowel Disease: Justification to Vaccinate at Diagnosis

Kantsø B, Simonsen J, Hoffmann S, et al. Inflammatory bowel disease patients are at increased risk of invasive pneumococcal disease: a nationwide Danish cohort study 1977-2013. Am J Gastroenterol 2015;110:1582–1587. Continue reading

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Pneumococcal Disease in Inflammatory Bowel Disease: Justification to Vaccinate at Diagnosis

Kantsø B, Simonsen J, Hoffmann S, et al. Inflammatory bowel disease patients are at increased risk of invasive pneumococcal disease: a nationwide Danish cohort study 1977-2013. Am J Gastroenterol 2015;110:1582–1587. Continue reading

Posted in News | Comments Off on Pneumococcal Disease in Inflammatory Bowel Disease: Justification to Vaccinate at Diagnosis