Daily Archives: June 30, 2016

The Esophageal Microbiome in Eosinophilic Esophagitis

Benitez AJ, Hoffman C, Muir AB, et al. Inflammation-associated microbiota in pediatric eosinophilic esophagitis. Microbiome 2015;3:23. Continue reading

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The Esophageal Microbiome in Eosinophilic Esophagitis

Benitez AJ, Hoffman C, Muir AB, et al. Inflammation-associated microbiota in pediatric eosinophilic esophagitis. Microbiome 2015;3:23. Continue reading

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Hepatitis C Virus RNA Persists in Liver Explants of Most Patients Awaiting Liver Transplantation Treated With an Interferon-Free Regimen

We assessed the presence of hepatitis C virus (HCV) RNA in liver explants from 39 patients awaiting liver transplantation who were treated with an interferon-free regimen and had undetectable serum HCV RNA at the time of liver transplantation. Interest… Continue reading

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HCV RNA Persists in Liver Explants of Most Patients Awaiting Liver Transplantation Treated With an Interferon-Free Regimen

We assessed the presence of hepatitis C virus (HCV) RNA in liver explants from 39 patients awaiting liver transplantation who were treated with an interferon-free regimen and had undetectable serum HCV RNA at the time of liver transplantation. Interest… Continue reading

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Mechanisms of Acetaminophen Hepatotoxicity: Do We Need JNK for Cell Death?

During the last decade, c-jun N-terminal kinase (Jnk) emerged as central player in the pathophysiology of acetaminophen (APAP)-induced liver injury, especially in mice.1,2 Jnk activation and translocation of phosphorylated-Jnk (p-Jnk) to mitochondria w… Continue reading

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Mechanisms of Acetaminophen Hepatotoxicity: Do We Need JNK for Cell Death?

During the last decade, c-jun N-terminal kinase (Jnk) emerged as central player in the pathophysiology of acetaminophen (APAP)-induced liver injury, especially in mice.1,2 Jnk activation and translocation of phosphorylated-Jnk (p-Jnk) to mitochondria w… Continue reading

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An Unusual Cause of Recurrent Dysphagia

Question: A 40-year-old woman, G2P0 at 11+6 gestational age, presented to the emergency department with a 1-week history of severe nausea and bilious vomiting with an inability to tolerate oral intake. She had been treated in the emergency department o… Continue reading

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An Unusual Cause of Recurrent Dysphagia

Question: A 40-year-old woman, G2P0 at 11+6 gestational age, presented to the emergency department with a 1-week history of severe nausea and bilious vomiting with an inability to tolerate oral intake. She had been treated in the emergency department o… Continue reading

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A Peculiar Lump in the Throat

Question: A 64-year-old woman was referred to the gastroenterology service with an 18-month history of pharyngeal foreign body sensation. She reported regurgitation of a “cylindrical mass” with a choking sensation. Abdominal, head, and neck examin… Continue reading

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A Peculiar Lump in the Throat

Question: A 64-year-old woman was referred to the gastroenterology service with an 18-month history of pharyngeal foreign body sensation. She reported regurgitation of a “cylindrical mass” with a choking sensation. Abdominal, head, and neck examin… Continue reading

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