Monthly Archives: July 2016
Rectal Indomethacin to Prevent Post-ERCP Pancreatitis
We read with great interest the study by Levenick et al1 on the utility of rectal indomethacin in consecutive patients to prevent post-ERCP pancreatitis (PEP). We congratulate the authors on their publication, but query some additional limitations tha… Continue reading
Should We Still Administer Prophylactic Rectal NSAIDs to Average-Risk Patients Undergoing ERCP?
The role of rectal nonsteroidal anti-inflammatory drugs (NSAIDs) for preventing pancreatitis in average-risk endoscopic retrograde cholangiopancreatography (ERCP) cases remains controversial. Although the European Society of Gastrointestinal Endoscopy … Continue reading
Complications and Anesthesia for Colonoscopy: Culprit or Accomplice?
I read with great interest the recent paper by Wernli et al1 and its accompanying editorial.2 As a practicing anesthesiologist, it is always interesting to read other specialties’ literature involving my own specialty. I believe, however, that this … Continue reading
Efficacy of Sofosbuvir, Velpatasvir, and GS-9857 in Patients with HCV Genotype 2, 3, 4, or 6 Infections in an Open-label, Phase 2 Trial
Studies are needed to determine the optimal regimen for patients with chronic hepatitis C virus (HCV) genotype 2, 3, 4, or 6 infections who have failed by a prior course of antiviral therapy, and the feasibility of further shortening treatment duration… Continue reading
Efficacy of Sofosbuvir, Velpatasvir, and GS-9857 in Patients with Genotype 1 Hepatitis C Virus Infection in an Open-label, Phase 2 Trial
The best regimen to retreat patients who do not respond to direct-acting antivirals (DAAs) and the feasibility of further shortening regimens is unclear. We assessed the efficacy and safety of the combination of the nucleotide polymerase inhibitor sofo… Continue reading
Anesthesia Services Are Beneficial for Colonoscopy in Interventional Gastroenterology
We read with great interest the article by Wernli et al1 regarding anesthesia services for colonoscopy. The authors conclude that the “overall risk of complications following colonoscopy increases when individuals receive anesthesia services.” We … Continue reading
Painful Anterior Chest Wall Mass, Compatible With Abscess on Computed Tomography and Possible Osteomyelitis in a Man With Ulcerative Colitis
Question: A 49-year-old man with history of ulcerative colitis and chronic anemia presented to the emergency department with complaints of pain and swelling on his chest, rapidly increasing in size for 2–3 days. He also complained of painful swelling… Continue reading
Anesthesia Services Increase Risk Of Complications After Colonoscopy: We Are Not Sure!
Colonoscopy is one of the most common screening tests for colorectal cancer worldwide.1 Despite the advance in perioperative care, colonoscopy screening still exposes patients to risk of complications and even harms. Anesthesiologists play an increasin… Continue reading
A Rare Cause of Gastrointestinal Ulcers
Question: A 48-year-old man was referred to our hospital for further evaluation and treatment of recurrent abdominal pain and hematochezia. He was treated 15 years ago with interferon alpha for infection with hepatitis C virus (HCV) genotype 1; however… Continue reading
Anesthesia’s Impact on Outcomes After Endoscopy: More Research Is Needed
We read with interest the recent study by Wernli et al1 describing a large retrospective analysis of >3 million patients to asses the relative risks of anesthesia services during colonoscopy. The authors correctly highlight the importance of this issue; anesthesia services are now employed in nearly 50% of cases. Although the results of the study provide us greater insights into the gastrointestinal (GI) practices across the country, we are concerned that the methodologic limitations of the study may lead some to misinterpret the findings. Continue reading