Daily Archives: July 30, 2016

Complications and Anesthesia for Colonoscopy: Culprit or Accomplice?

I read with great interest the recent paper by Wernli et al1 and its accompanying editorial.2 As a practicing anesthesiologist, it is always interesting to read other specialties’ literature involving my own specialty. I believe, however, that this … Continue reading

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Efficacy of Sofosbuvir, Velpatasvir, and GS-9857 in Patients with HCV Genotype 2, 3, 4, or 6 Infections in an Open-label, Phase 2 Trial

Studies are needed to determine the optimal regimen for patients with chronic hepatitis C virus (HCV) genotype 2, 3, 4, or 6 infections who have failed by a prior course of antiviral therapy, and the feasibility of further shortening treatment duration… Continue reading

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Efficacy of Sofosbuvir, Velpatasvir, and GS-9857 in Patients with Genotype 1 Hepatitis C Virus Infection in an Open-label, Phase 2 Trial

The best regimen to retreat patients who do not respond to direct-acting antivirals (DAAs) and the feasibility of further shortening regimens is unclear. We assessed the efficacy and safety of the combination of the nucleotide polymerase inhibitor sofo… Continue reading

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Anesthesia Services Are Beneficial for Colonoscopy in Interventional Gastroenterology

We read with great interest the article by Wernli et al1 regarding anesthesia services for colonoscopy. The authors conclude that the “overall risk of complications following colonoscopy increases when individuals receive anesthesia services.” We … Continue reading

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Painful Anterior Chest Wall Mass, Compatible With Abscess on Computed Tomography and Possible Osteomyelitis in a Man With Ulcerative Colitis

Question: A 49-year-old man with history of ulcerative colitis and chronic anemia presented to the emergency department with complaints of pain and swelling on his chest, rapidly increasing in size for 2–3 days. He also complained of painful swelling… Continue reading

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Anesthesia Services Increase Risk Of Complications After Colonoscopy: We Are Not Sure!

Colonoscopy is one of the most common screening tests for colorectal cancer worldwide.1 Despite the advance in perioperative care, colonoscopy screening still exposes patients to risk of complications and even harms. Anesthesiologists play an increasin… Continue reading

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A Rare Cause of Gastrointestinal Ulcers

Question: A 48-year-old man was referred to our hospital for further evaluation and treatment of recurrent abdominal pain and hematochezia. He was treated 15 years ago with interferon alpha for infection with hepatitis C virus (HCV) genotype 1; however… Continue reading

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Anesthesia’s Impact on Outcomes After Endoscopy: More Research Is Needed

We read with interest the recent study by Wernli et al1 describing a large retrospective analysis of >3 million patients to asses the relative risks of anesthesia services during colonoscopy. The authors correctly highlight the importance of this issue; anesthesia services are now employed in nearly 50% of cases. Although the results of the study provide us greater insights into the gastrointestinal (GI) practices across the country, we are concerned that the methodologic limitations of the study may lead some to misinterpret the findings. Continue reading

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Rectal Indomethacin for the Prevention of Post-ERCP Pancreatitis

We have read with great interest the article of Levenick et al. in the recent issue of Gastroenterology on the effect of rectal indomethacin for the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP).1 The auth… Continue reading

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Covering the Cover

In this Markov model of average-risk colorectal cancer screening, annual fecal immunohistochemical testing or colonoscopy every 10 years was more effective and less costly compared with multitarget stool DNA testing every 3 years. Continue reading

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