Monthly Archives: July 2016

We have read with great interest the article of Levenick et al. in the recent issue of Gastroenterology on the effect of rectal indomethacin for the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP).1 The auth… Continue reading →

In this Markov model of average-risk colorectal cancer screening, annual fecal immunohistochemical testing or colonoscopy every 10 years was more effective and less costly compared with multitarget stool DNA testing every 3 years. Continue reading →

When the new operating system “Windows 10” was released, reviewer Walt Mossberg commented that “Microsoft takes a step back to move forward.”1 In this same regard, forward progress of sedation for gastrointestinal (GI) endoscopy requires taking… Continue reading →

Question: A 15-year-old boy with severe mental retardation associated with Dravet syndrome was referred to the emergency room for acute gastroenteritis. At that time, abdominal radiograph showed a concentration of contrast in the right lower quadrant … Continue reading →

We read with great interest the study by Levenick et al entitled, “Rectal Indomethacin Does not Prevent Post-ERCP Pancreatitis in Consecutive Patients.”1 The authors evaluated the efficacy of rectal indomethacin vs placebo for the prevention of po… Continue reading →

The article by Wernli et al1 in the April issue of Gastroenterology is important because it demonstrates an association between use of anesthesia services and increased 30-day colonoscopy complication rates, but is subject to several criticisms. First… Continue reading →

Jensen CD, Corley DA, Quinn VP, et al. Fecal immunochemical test program performance over 4 rounds of annual screening: a retrospective cohort study. Ann Intern Med 2016;164:456–463. Continue reading →

The gastrointestinal (GI), pancreatic, and hepatic systems work in concert to break down and absorb nutrients, maintain homeostatic glucose levels, and purify the entire bodily organism. Unfortunately, these systems are plagued by many debilitating and… Continue reading →

The 5-hydroxytryptamine receptor 4 (5-HT4R or HTR4) is expressed in the colonic epithelium but little is known about its functions there. We examined whether activation of colonic epithelial 5-HT4R protects colons of mice from inflammation. Continue reading →