Monthly Archives: July 2016

Inflammation and the Intestinal Barrier: Leukocyte–Epithelial Cell Interactions, Cell Junction Remodeling, and Mucosal Repair

Posted on July 16, 2016 by Anny-Claude Luissint, Charles A. Parkos, Asma Nusrat

The intestinal tract is lined by a single layer of columnar epithelial cells that forms a dynamic, permeable barrier allowing for selective absorption of nutrients while restricting access to pathogens and food-borne antigens. Precise regulation of epi… Continue reading →

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Antibiotics Suppress Activation of Intestinal Mucosal Mast Cells and Reduce Dietary Lipid Absorption in Sprague-Dawley Rats

Posted on July 16, 2016 by Hirokazu Sato, Linda S. Zhang, Kristina Martinez, Eugene B. Chang, Qing Yang, Fei Wang, Philip N. Howles, Ryota Hokari, Soichiro Miura, Patrick Tso

The gut microbiota affects intestinal permeability and mucosal mast cell (MMCs) responses. Activation of MMCs has been associated with absorption of dietary fat. We investigated whether the gut microbiota contributes to the fat-induced activation of MM… Continue reading →

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Antibiotics Suppress Activation of Intestinal Mucosal Mast Cells and Reduce Dietary Lipid Absorption in Sprague-Dawley Rats

Posted on July 16, 2016 by Hirokazu Sato, Linda S. Zhang, Kristina Martinez, Eugene B. Chang, Qing Yang, Fei Wang, Philip N. Howles, Ryota Hokari, Soichiro Miura, Patrick Tso

The gut microbiota affects intestinal permeability and mucosal mast cell (MMCs) responses. Activation of MMCs has been associated with absorption of dietary fat. We investigated whether the gut microbiota contributes to the fat-induced activation of MM… Continue reading →

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Compliance With and Timing of Prophylactic Antibiotic Administration and Risk of Peristomal Wound Infection After Percutaneous Endoscopic Gastrostomy

Posted on July 15, 2016 by Alisa Likhitsup, Devika Kapuria, Wendell K. Clarkston

Current guidelines suggest prophylactic antibiotics should be administered 30 minutes before percutaneous endoscopic gastrostomy (PEG) placement in order to reduce gastrostomy site infections. We observed variations in administration of prophylactic an… Continue reading →

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Reducing Medical Errors: Using Observed Standardized Clinical Examinations to Assess Fellows’ Performance in System-Based Practice Milestones

Posted on July 15, 2016 by Marianna Papademetriou, Gabriel Perreault, Colleen Gillespie, Sondra Zabar, Elizabeth Weinshel, Renee Williams

Medical training has increasingly focused on standardization to improve communication and reduce medical errors. In gastroenterology training programs, the need for clear interpersonal communication is heightened by the high acuity of patients and the … Continue reading →

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Patient Perception of Bowel Preparation for Colonoscopy in the Urban Tertiary Care Setting

Posted on July 15, 2016 by George K. John, Nitin K. Ahuja, Abhishek Agnihotri, Isabelita Ortiz, Mary Beth Carlin, Ellen Stein

Inadequate bowel preparation hampers visualization during colonoscopy, leading to missed lesions and the need to repeat screening colonoscopy. Patient perceptions and motivations can influence the quality of the bowel preparation as well as the likelih… Continue reading →

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Quality Indicators in Pediatric Digestive Endoscopy: Lessons Learned From a High-Volume Endoscopy Unit

Posted on July 15, 2016 by Anne-Sophie Groleau, Mélissandre Ostiguy, Dieudonné Soubeiga, Patricia Perreault, Jessica Ezri, Stéphanie Berthet, Hélène Restieri, Véronique Groleau, Martha Dirks, Eric Drouin, Prévost Jantchou

Pediatric gastrointestinal endoscopy must be performed by an experienced operator within an appropriate environment for the safety of patients. Studies evaluating the quality and safety of pediatric endoscopy are scarce and none has attempted to evalua… Continue reading →

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Adherence to Clostridium difficile Infection Treatment Guidelines at a Tertiary Care Hospital: A Retrospective Chart Review

Posted on July 15, 2016 by Christine Granato, Xiang Lu, Sally Thurston, Danielle Marino

Morbidity secondary to Clostridium difficile infection (CDI) places a burden on the health care system. Updated practice guidelines for CDI have been published by the Infectious Diseases Society of America in 2010, with a supplement published in 2013 b… Continue reading →

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Unraveling a Patient’s Post-Op Symptoms

Posted on July 3, 2016 by Andrew C. Storm, Christopher C. Thompson

A 45-year-old female with history of morbid obesity status post Roux-en-Y gastric bypass (RYGB) six months ago for weight loss presents to the emergency department with acute on chronic abdominal pain. She reports that these upper gastrointestinal (UGI… Continue reading →

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Unraveling a Patient’s Post-Op Symptoms

Posted on July 3, 2016 by Andrew C. Storm, Christopher C. Thompson

A 45-year-old female with history of morbid obesity status post Roux-en-Y gastric bypass (RYGB) six months ago for weight loss presents to the emergency department with acute on chronic abdominal pain. She reports that these upper gastrointestinal (UGI… Continue reading →

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