Monthly Archives: July 2016
Covering the Cover
In this retrospective cohort study, continuation of low-dose aspirin use was associated with a nearly 3-fold increased risk of recurrent lower GI bleeding, but reduced risk of serious cardiovascular events and death. Continue reading
Covering the Cover
In this retrospective cohort study, continuation of low-dose aspirin use was associated with a nearly 3-fold increased risk of recurrent lower GI bleeding, but reduced risk of serious cardiovascular events and death. Continue reading
An Unusually Located Colonic Mass
Question: A 71-year-old man presented to the emergency department with episodic bright red blood per rectum. He reported that these episodes occur for 15-20 minutes per day for 1- to 2-week periods and usually resolve spontaneously, but that when he bl… Continue reading
An Unusually Located Colonic Mass
Question: A 71-year-old man presented to the emergency department with episodic bright red blood per rectum. He reported that these episodes occur for 15-20 minutes per day for 1- to 2-week periods and usually resolve spontaneously, but that when he bl… Continue reading
A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn’s Disease and Reduces Monocyte Signaling via GM-CSF
Crohn’s disease (CD) has the highest prevalence in Ashkenazi Jewish populations. We sought to identify rare, CD-associated frameshift variants of high functional and statistical effects. Continue reading
A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn’s Disease and Reduces Monocyte Signaling via GMCSF
Crohn’s disease associated frameshift mutation in CSF2RB results in decreased STAT5 activation in a dominant negative manner. Continue reading
Is Magnetic Resonance Imaging Really More Accurate for Classifying Steatosis Than Controlled Attenuation Parameter?
Imajo et al1 have undertaken the important task of analyzing non invasive surrogates for pathologically assessed liver fibrosis and steatosis.1 Regarding fibrosis, Bedossa et al2 are amongst those who have noted the “urgent need” for doing so and… Continue reading
Is Magnetic Resonance Imaging Really More Accurate for Classifying Steatosis Than Controlled Attenuation Parameter?
Imajo et al1 have undertaken the important task of analyzing non invasive surrogates for pathologically assessed liver fibrosis and steatosis.1 Regarding fibrosis, Bedossa et al2 are amongst those who have noted the “urgent need” for doing so and… Continue reading
Reply
We were pleased to read Karlas and Petroff’s comments addressing our article comparing magnetic resonance imaging (MRI) and transient elastography (TE) using the M probe for staging of liver fibrosis and grading steatosis in nonalcoholic fatty liver … Continue reading
Reply
We were pleased to read Karlas and Petroff’s comments addressing our article comparing magnetic resonance imaging (MRI) and transient elastography (TE) using the M probe for staging of liver fibrosis and grading steatosis in nonalcoholic fatty liver … Continue reading