Daily Archives: August 6, 2016

Pancreatic Pre-malignant Lesions Secrete TIMP1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Pre-Metastatic Niche in the Liver

Posted on August 6, 2016 by Gastroenterology Journal

Pancreatic ductal adenocarcinoma (PDAC) metastasizes to liver at early stages, making this disease highly lethal. TIMP metallopeptidase inhibitor 1 (TIMP1) creates a metastasis-susceptible environment in the liver. We investigated the role of TIMP1 and… Continue reading →

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Pancreatic Pre-malignant Lesions Secrete TIMP1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Pre-Metastatic Niche in the Liver

Posted on August 6, 2016 by Gastroenterology Journal

Pancreatic ductal adenocarcinoma (PDAC) metastasizes to liver at early stages, making this disease highly lethal. TIMP metallopeptidase inhibitor 1 (TIMP1) creates a metastasis-susceptible environment in the liver. We investigated the role of TIMP1 and… Continue reading →

Posted in News | Comments Off on Pancreatic Pre-malignant Lesions Secrete TIMP1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Pre-Metastatic Niche in the Liver