Question: A 53-year-old man presented with a 3-day history of odynophagia. His medical history was significant for multiple episodes of azole-resistant esophageal candidiasis, human immunodeficiency virus–hepatitis C virus coinfection (with a CD4 count of 40, and a viral load of 500,000), pneumocystis pneumonia, a history of substance abuse now on methadone maintenance, and tobacco abuse. On this admission, he reported pain in his mid-sternal and mid-epigastric region associated with a feeling of solid food getting stuck.