Monthly Archives: August 2016
Appropriate Timing of Rectal Indomethacin Administration and Patient Selection in Assessment of Post-ERCP Pancreatitis
We read with great interest the article by Levenick et al,1 who evaluated the efficacy of indomethacin given via the rectal route in preventing post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) in a randomized controlled tr… Continue reading
A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn’s Disease and Human Gut Microbiome Composition
Genome-wide association studies have identified 200 inflammatory bowel disease (IBD) loci, but the genetic architecture of Crohn’s disease (CD) and ulcerative colitis remain incompletely defined. Here, we aimed to identify novel associations between … Continue reading
An Unusual Cause of Life-Threatening Upper Gastrointestinal Bleeding
Question: A 56-year-old man was admitted to our emergency department because of a transient loss of consciousness. He had been suffering from dizziness and melena for two weeks and denied any use of nonsteroidal anti-inflammatory drugs or anticoagulant… Continue reading
Alcohol Consumption and Multiple Dysplastic Lesions Increase Risk of Squamous Cell Carcinoma in the Esophagus, Head, and Neck
Some patients develop multiple squamous cell carcinomas (SCCs) in the upper aero-digestive tract, attributed to field cancerization; alcohol consumption has been associated with this process. We examined the association between multiple areas of dyspla… Continue reading
An Unusual Cause of Hematochezia and Aneurysmal Small Bowel Dilatation
Question: A 73-year-old man with a history of hypertension presented with the first attack of approximately 300 mL volume of hematochezia. The patient was afebrile with stable vital sign and physical examination was normal. The laboratory test showed t… Continue reading
Unusual Gastric Nodules
Question: A 70-year-old man from Italy presented with dyspnea, fainting, and coughing. His medical history includes diabetes, hypertension, hyperlipidemia, and morbid obesity. On physical examination, he had pale conjunctiva and systolic heart murmur. … Continue reading