Monthly Archives: September 2016
Association of Proton Pump Inhibitors with Reduced Risk of Warfarin-related Serious Upper Gastrointestinal Bleeding
Proton-pump inhibitors (PPIs) might reduce the risk of serious warfarin-related upper gastrointestinal bleeding, but the evidence of their efficacy for this indication is limited. A gastroprotective effect of PPIs would be particularly important for pa… Continue reading
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Rectal Delivery of a DNAzyme That Specifically Blocks the Transcription Factor GATA3 and Reduces Colitis in Mice
GATA3 is a transcription factor that regulates T-cell production of cytokines. We investigated the role of GATA3 in development of colitis in mice. Continue reading
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Rectal Delivery of a DNAzyme That Specifically Blocks the Transcription Factor GATA3 Reduces Colitis in Mice
GATA3 is a transcription factor that regulates T-cell production of cytokines. We investigated the role of GATA3 in development of colitis in mice. Continue reading
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EUS-guided methylene blue injection to facilitate pancreatic duct access after unsuccessful ERCP
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EUS-guided methylene blue injection to facilitate pancreatic duct access after unsuccessful ERCP
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Cell Culture System for Analysis of Genetic Heterogeneity Within Hepatocellular Carcinomas and Response to Pharmacologic Agents
No targeted therapies have been found to be effective against hepatocellular carcinoma (HCC), possibly due to the large degree of intratumor heterogeneity. We performed genetic analyses of different regions of HCCs to evaluate levels of intratumor hete… Continue reading
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Cell Culture System for Analysis of Genetic Heterogeneity Within Hepatocellular Carcinomas and Response to Pharmacologic Agents
No targeted therapies have been found to be effective against hepatocellular carcinoma (HCC), possibly due to the large degree of intratumor heterogeneity. We performed genetic analyses of different regions of HCCs to evaluate levels of intratumor hete… Continue reading
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Le Gac et al and Bignell et al reported data that strongly support our results showing the role of heterozygous BMP6 mutations in mild-to-moderate late-onset iron overload with variable phenotype depending on age, sex, as well as genetic and environm… Continue reading
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Le Gac et al and Bignell et al reported data that strongly support our results showing the role of heterozygous BMP6 mutations in mild-to-moderate late-onset iron overload with variable phenotype depending on age, sex, as well as genetic and environm… Continue reading
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IGF2 is Upregulated by Epigenetic Mechanisms in Hepatocellular Carcinomas and is an Actionable Oncogene Product in Experimental Models
Effective treatments are urgently needed for hepatocellular carcinoma (HCC), which is usually diagnosed at advanced stages. Signaling via the insulin-like growth factor (IGF) pathway is aberrantly activated in HCC by IGF2 overexpression. We aimed to el… Continue reading
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